| Summary: | The aim was to study the feasibility of syntax score calculation with Multislice Computed Tomographic Angiography (MSCTA).
Methods: Syntax score was calculated and compared for 91 consecutive patients underwent MSCTA and Invasive coronary angiography (ICA).
Results: MSCTA for the diagnosis of >50 % stenosis per coronary artery showed that MSCTA had a specificity, sensitivity, specificity, negative predictive value and accuracy of 92.2% (217/235), 97.1% (125/129), 98.2% (217/221), and 94.3% (364/386) respectively. Agreement between modalities was high with a kappa of 0.74. There was a positive correlation between MSCTA and ICA Syntax scores (r = 0.73, p = 0.000). The mean Syntax score was 15.8 ± 7.16 for ICA versus 16.3 ± 7.6 for MSCTA (Kappa of Cohen 0.66, p = 0.000). The Bland–Altman plot revealed that the estimated bias was 1.9 ± 3.4 and the most bias occurred with a higher syntax score. Lesions per patient were more identified with MSCTA than ICA (2.5 ± 1.4 vs. 1.9 ± 1.1, p < 0.001), with a good level of agreement (kappa = 0.65). Syntax score per lesion was similar with a high level of agreement (6.3 ± 5.8 vs. 6.0 ± 4.8, kappa = 0.74, p < 0.001). Calcified lesions were identified to a similar extent (28 vs. 26 cases) with a fair level of agreement (kappa = 0.42). Lesions identified with both techniques showed a higher level of agreement than the total score (6.5 ± 4.8 for MSCTA vs. 6.9 ± 6.3 for ICA, p < 0.05), kappa = 0.76.
Conclusion: MSCTA showed a good level of agreement with ICA in syntax score calculation.
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