Selenoproteins in Health

Selenium (Se) is a naturally occurring essential micronutrient that is required for human health. The existing form of Se includes inorganic and organic. In contrast to the inorganic Se, which has low bioavailability and high cytotoxicity, organic Se exhibits higher bioavailability, lower toxicity,...

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Main Authors: Ziqi Qi, Alex Duan, Ken Ng
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/1/136
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author Ziqi Qi
Alex Duan
Ken Ng
author_facet Ziqi Qi
Alex Duan
Ken Ng
author_sort Ziqi Qi
collection DOAJ
description Selenium (Se) is a naturally occurring essential micronutrient that is required for human health. The existing form of Se includes inorganic and organic. In contrast to the inorganic Se, which has low bioavailability and high cytotoxicity, organic Se exhibits higher bioavailability, lower toxicity, and has a more diverse composition and structure. This review presents the nutritional benefits of Se by listing and linking selenoprotein (SeP) functions to evidence of health benefits. The research status of SeP from foods in recent years is introduced systematically, particularly the sources, biochemical transformation and speciation, and the bioactivities. These aspects are elaborated with references for further research and utilization of organic Se compounds in the field of health.
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spelling doaj.art-391c9700853d4812ba332655e03bac9a2024-01-10T15:04:16ZengMDPI AGMolecules1420-30492023-12-0129113610.3390/molecules29010136Selenoproteins in HealthZiqi Qi0Alex Duan1Ken Ng2School of Agriculture, Food and Ecosystem Sciences, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, AustraliaMelbourne TrACEES Platform, School of Chemistry, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, AustraliaSchool of Agriculture, Food and Ecosystem Sciences, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, AustraliaSelenium (Se) is a naturally occurring essential micronutrient that is required for human health. The existing form of Se includes inorganic and organic. In contrast to the inorganic Se, which has low bioavailability and high cytotoxicity, organic Se exhibits higher bioavailability, lower toxicity, and has a more diverse composition and structure. This review presents the nutritional benefits of Se by listing and linking selenoprotein (SeP) functions to evidence of health benefits. The research status of SeP from foods in recent years is introduced systematically, particularly the sources, biochemical transformation and speciation, and the bioactivities. These aspects are elaborated with references for further research and utilization of organic Se compounds in the field of health.https://www.mdpi.com/1420-3049/29/1/136seleniumselenoproteinbioaccessibilitybioactivityfood resources
spellingShingle Ziqi Qi
Alex Duan
Ken Ng
Selenoproteins in Health
Molecules
selenium
selenoprotein
bioaccessibility
bioactivity
food resources
title Selenoproteins in Health
title_full Selenoproteins in Health
title_fullStr Selenoproteins in Health
title_full_unstemmed Selenoproteins in Health
title_short Selenoproteins in Health
title_sort selenoproteins in health
topic selenium
selenoprotein
bioaccessibility
bioactivity
food resources
url https://www.mdpi.com/1420-3049/29/1/136
work_keys_str_mv AT ziqiqi selenoproteinsinhealth
AT alexduan selenoproteinsinhealth
AT kenng selenoproteinsinhealth