Oxidative stress and Antioxidant Defense Mechanisms in Dentistry: A Literature Review
This review paper aimed to evaluate the effect of oxidative stress in the prevalence of somedental diseases and the role of antioxidants in dentistry. Oxidative stress is a normal phenomenon, present in healthy human body help them to produce energy that they need for their life. During that, the f...
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| Format: | Article |
| Language: | Arabic |
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University of Mosul, College of Dentistry
2022-09-01
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| Series: | Al-Rafidain Dental Journal |
| Subjects: | |
| Online Access: | https://rden.mosuljournals.com/pdf_175960_f2dfb53fb06dda695a3929a4d1c43a0d.html |
| Summary: | This review paper aimed to evaluate the effect of oxidative stress in the prevalence of somedental diseases and the role of antioxidants in dentistry. Oxidative stress is a normal
phenomenon, present in healthy human body help them to produce energy that they need for their life. During that, the formation of free radicals begins, including both reactive oxygen
species "ROS" & also reactive nitrogen species "RNS". These radicals have a role in a many types of signalling pathways that regulate inflammation. Antioxidants constrain the formation of free radicals. Mitochondria, a small cell organelle acts to generate energy in the form of adenosine triphosphate "ATP". It combines oxygen & glucose to form carbon dioxide, water, & ATP. Free radicals result as by-products of this metabolic process & when
natural defense apparatuses be unsuccessful, the level of free radicals begins to increase to levels where the capacity of the body is unable to neutralize them entering the body into the
state of high oxidative stress, which means greater risk of numerous oral & systemic diseases. Oral tissues are liable to free radical damage in a unique manner due to the presence of mucus membranes that allow rapid absorption of constituents throughout their surfaces. In oral environment, infection of gingiva can produce oxidative stress. The rise in formation
of free radicals by oxidative stress results in further destruction of cellular walls and oral tissues. The study results suggested that the use of antioxidants is an adjunct approach to dental therapy may be helpful in controlling the oral health status. |
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| ISSN: | 1812-1217 1998-0345 |