Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer
Understanding the heterogeneity of growth, response to therapy and progression dynamics in metastatic colorectal cancer (mCRC) remains critical. Here, the authors analyse lesion-specific response heterogeneity in 4,308 mCRC patients and find that organ-level progression sequence is associated with l...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-36121-y |
| _version_ | 1811175800664227840 |
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| author | Jiawei Zhou Amber Cipriani Yutong Liu Gang Fang Quefeng Li Yanguang Cao |
| author_facet | Jiawei Zhou Amber Cipriani Yutong Liu Gang Fang Quefeng Li Yanguang Cao |
| author_sort | Jiawei Zhou |
| collection | DOAJ |
| description | Understanding the heterogeneity of growth, response to therapy and progression dynamics in metastatic colorectal cancer (mCRC) remains critical. Here, the authors analyse lesion-specific response heterogeneity in 4,308 mCRC patients and find that organ-level progression sequence is associated with long-term survival. |
| first_indexed | 2024-04-10T19:41:46Z |
| format | Article |
| id | doaj.art-3920660bc9774fe5af13df5d3accd7dc |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T19:41:46Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3920660bc9774fe5af13df5d3accd7dc2023-01-29T12:16:21ZengNature PortfolioNature Communications2041-17232023-01-0114111210.1038/s41467-023-36121-yMapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancerJiawei Zhou0Amber Cipriani1Yutong Liu2Gang Fang3Quefeng Li4Yanguang Cao5Division of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, University of North Carolina at Chapel HillDivision of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, University of North Carolina at Chapel HillSchool of Public Health, University of North Carolina at Chapel HillDivision of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina at Chapel HillSchool of Public Health, University of North Carolina at Chapel HillDivision of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, University of North Carolina at Chapel HillUnderstanding the heterogeneity of growth, response to therapy and progression dynamics in metastatic colorectal cancer (mCRC) remains critical. Here, the authors analyse lesion-specific response heterogeneity in 4,308 mCRC patients and find that organ-level progression sequence is associated with long-term survival.https://doi.org/10.1038/s41467-023-36121-y |
| spellingShingle | Jiawei Zhou Amber Cipriani Yutong Liu Gang Fang Quefeng Li Yanguang Cao Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer Nature Communications |
| title | Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer |
| title_full | Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer |
| title_fullStr | Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer |
| title_full_unstemmed | Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer |
| title_short | Mapping lesion-specific response and progression dynamics and inter-organ variability in metastatic colorectal cancer |
| title_sort | mapping lesion specific response and progression dynamics and inter organ variability in metastatic colorectal cancer |
| url | https://doi.org/10.1038/s41467-023-36121-y |
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