Structure of the Neisseria meningitidis Type IV pilus
Type IV pili are present on a wide range of bacterial pathogens and mediate diverse functions. Here the authors report a high resolution crystal structure of the pilin subunit PilE, and a cryoEM reconstruction of the Type IV pilus filament from N. meningitidisthat offer insight into pilus assembly a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms13015 |
| _version_ | 1818978094884585472 |
|---|---|
| author | Subramania Kolappan Mathieu Coureuil Xiong Yu Xavier Nassif Edward H. Egelman Lisa Craig |
| author_facet | Subramania Kolappan Mathieu Coureuil Xiong Yu Xavier Nassif Edward H. Egelman Lisa Craig |
| author_sort | Subramania Kolappan |
| collection | DOAJ |
| description | Type IV pili are present on a wide range of bacterial pathogens and mediate diverse functions. Here the authors report a high resolution crystal structure of the pilin subunit PilE, and a cryoEM reconstruction of the Type IV pilus filament from N. meningitidisthat offer insight into pilus assembly and functions. |
| first_indexed | 2024-12-20T16:38:11Z |
| format | Article |
| id | doaj.art-39246ee32583442596e6d29879d5c289 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T16:38:11Z |
| publishDate | 2016-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-39246ee32583442596e6d29879d5c2892022-12-21T19:33:05ZengNature PortfolioNature Communications2041-17232016-10-017111210.1038/ncomms13015Structure of the Neisseria meningitidis Type IV pilusSubramania Kolappan0Mathieu Coureuil1Xiong Yu2Xavier Nassif3Edward H. Egelman4Lisa Craig5Department of Molecular Biology and Biochemistry, Simon Fraser UniversityInstitut Necker-Enfants Malades, INSERM U1151, Université Paris Descartes, 14 Rue Maria Helena Vieira Da Silva, CS 61431Department of Biochemistry and Molecular Genetics, University of Virginia School of MedicineInstitut Necker-Enfants Malades, INSERM U1151, Université Paris Descartes, 14 Rue Maria Helena Vieira Da Silva, CS 61431Department of Biochemistry and Molecular Genetics, University of Virginia School of MedicineDepartment of Molecular Biology and Biochemistry, Simon Fraser UniversityType IV pili are present on a wide range of bacterial pathogens and mediate diverse functions. Here the authors report a high resolution crystal structure of the pilin subunit PilE, and a cryoEM reconstruction of the Type IV pilus filament from N. meningitidisthat offer insight into pilus assembly and functions.https://doi.org/10.1038/ncomms13015 |
| spellingShingle | Subramania Kolappan Mathieu Coureuil Xiong Yu Xavier Nassif Edward H. Egelman Lisa Craig Structure of the Neisseria meningitidis Type IV pilus Nature Communications |
| title | Structure of the Neisseria meningitidis Type IV pilus |
| title_full | Structure of the Neisseria meningitidis Type IV pilus |
| title_fullStr | Structure of the Neisseria meningitidis Type IV pilus |
| title_full_unstemmed | Structure of the Neisseria meningitidis Type IV pilus |
| title_short | Structure of the Neisseria meningitidis Type IV pilus |
| title_sort | structure of the neisseria meningitidis type iv pilus |
| url | https://doi.org/10.1038/ncomms13015 |
| work_keys_str_mv | AT subramaniakolappan structureoftheneisseriameningitidistypeivpilus AT mathieucoureuil structureoftheneisseriameningitidistypeivpilus AT xiongyu structureoftheneisseriameningitidistypeivpilus AT xaviernassif structureoftheneisseriameningitidistypeivpilus AT edwardhegelman structureoftheneisseriameningitidistypeivpilus AT lisacraig structureoftheneisseriameningitidistypeivpilus |