Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia

Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia

Abstract Background T cell acute lymphoblastic leukemia (T-ALL) defines a group of hematological malignancies with heterogeneous aggressiveness and highly variable outcome, making therapeutic decisions a challenging task. We tried to discover new predictive model for T-ALL before treatment by using...

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Bibliographic Details
Main Authors: Li-Jun Peng, Yue-Bo Zhou, Mei Geng, Ekaterina Bourova-Flin, Florent Chuffart, Wei-Na Zhang, Tao Wang, Meng-Qing Gao, Meng-Ping Xi, Zhong-Yi Cheng, Jiao-Jiao Zhang, Yuan-Fang Liu, Bing Chen, Saadi Khochbin, Jin Wang, Sophie Rousseaux, Jian-Qing Mi
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Genomics
Subjects:
T-ALL
Tissue-specific genes
Prognosis
Transcriptomic profile
Online Access:https://doi.org/10.1186/s12864-022-08688-1

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