miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway

miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway

Abstract Background We have previously verified the beneficial effects of exosomes from endothelial progenitor cells (EPC-EXs) in ischemic stroke. However, the effects of EPC-EXs in hemorrhagic stroke have not been investigated. Additionally, miR-137 is reported to regulate ferroptosis and to be inv...

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Bibliographic Details
Main Authors: Yuchen Li, Jinju Wang, Shuzhen Chen, Pei Wu, Shancai Xu, Chunlei Wang, Huaizhang Shi, Ji Bihl
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Stem Cell Research & Therapy
Subjects:
miR-137
Oxyhemoglobin
Exosomes
COX2
Ferroptosis
Online Access:http://link.springer.com/article/10.1186/s13287-020-01836-y

Internet

http://link.springer.com/article/10.1186/s13287-020-01836-y

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