Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering

Cardiovascular diseases are the leading cause of morbidity and mortality in the United States. Cardiac tissue engineering is a direction in regenerative medicine that aims to repair various heart defects with the long-term goal of artificially rebuilding a full-scale organ that matches its native st...

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Main Authors: Catherine A. Wu, Yuanjia Zhu, Y. Joseph Woo
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/7/842
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author Catherine A. Wu
Yuanjia Zhu
Y. Joseph Woo
author_facet Catherine A. Wu
Yuanjia Zhu
Y. Joseph Woo
author_sort Catherine A. Wu
collection DOAJ
description Cardiovascular diseases are the leading cause of morbidity and mortality in the United States. Cardiac tissue engineering is a direction in regenerative medicine that aims to repair various heart defects with the long-term goal of artificially rebuilding a full-scale organ that matches its native structure and function. Three-dimensional (3D) bioprinting offers promising applications through its layer-by-layer biomaterial deposition using different techniques and bio-inks. In this review, we will introduce cardiac tissue engineering, 3D bioprinting processes, bioprinting techniques, bio-ink materials, areas of limitation, and the latest applications of this technology, alongside its future directions for further innovation.
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spelling doaj.art-392d3779bd1645349fa7169c40fc78892023-11-18T18:22:07ZengMDPI AGBioengineering2306-53542023-07-0110784210.3390/bioengineering10070842Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue EngineeringCatherine A. Wu0Yuanjia Zhu1Y. Joseph Woo2Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USADepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USADepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USACardiovascular diseases are the leading cause of morbidity and mortality in the United States. Cardiac tissue engineering is a direction in regenerative medicine that aims to repair various heart defects with the long-term goal of artificially rebuilding a full-scale organ that matches its native structure and function. Three-dimensional (3D) bioprinting offers promising applications through its layer-by-layer biomaterial deposition using different techniques and bio-inks. In this review, we will introduce cardiac tissue engineering, 3D bioprinting processes, bioprinting techniques, bio-ink materials, areas of limitation, and the latest applications of this technology, alongside its future directions for further innovation.https://www.mdpi.com/2306-5354/10/7/842cardiac tissue engineeringbioprintingbiomaterialsbio-inks
spellingShingle Catherine A. Wu
Yuanjia Zhu
Y. Joseph Woo
Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering
Bioengineering
cardiac tissue engineering
bioprinting
biomaterials
bio-inks
title Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering
title_full Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering
title_fullStr Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering
title_full_unstemmed Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering
title_short Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering
title_sort advances in 3d bioprinting techniques applications and future directions for cardiac tissue engineering
topic cardiac tissue engineering
bioprinting
biomaterials
bio-inks
url https://www.mdpi.com/2306-5354/10/7/842
work_keys_str_mv AT catherineawu advancesin3dbioprintingtechniquesapplicationsandfuturedirectionsforcardiactissueengineering
AT yuanjiazhu advancesin3dbioprintingtechniquesapplicationsandfuturedirectionsforcardiactissueengineering
AT yjosephwoo advancesin3dbioprintingtechniquesapplicationsandfuturedirectionsforcardiactissueengineering