Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions
Abstract Introduction Levothyroxine, the standard-of-care treatment for hypothyroidism, is susceptible to degradation when exposed to light and moisture and is an FDA-designated narrow therapeutic index drug. In this report, we examined how different packaging (e.g., cold form blister packs, manufac...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-10-01
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| Series: | AAPS Open |
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| Online Access: | https://doi.org/10.1186/s41120-022-00062-5 |