Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans
Neck muscle activity evoked by vestibular stimuli is a clinical measure for evaluating the function of the vestibular apparatus. Cervical vestibular-evoked myogenic potentials (cVEMP) are most commonly measured in the sternocleidomastoid muscle (and more recently the splenius capitis muscle) in resp...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-07-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.00535/full |
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| author | Patrick A. Forbes Patrick A. Forbes Jason B. Fice Gunter P. Siegmund Gunter P. Siegmund Jean-Sébastien Blouin Jean-Sébastien Blouin Jean-Sébastien Blouin |
| author_facet | Patrick A. Forbes Patrick A. Forbes Jason B. Fice Gunter P. Siegmund Gunter P. Siegmund Jean-Sébastien Blouin Jean-Sébastien Blouin Jean-Sébastien Blouin |
| author_sort | Patrick A. Forbes |
| collection | DOAJ |
| description | Neck muscle activity evoked by vestibular stimuli is a clinical measure for evaluating the function of the vestibular apparatus. Cervical vestibular-evoked myogenic potentials (cVEMP) are most commonly measured in the sternocleidomastoid muscle (and more recently the splenius capitis muscle) in response to air-conducted sound, bone-conducted vibration or electrical vestibular stimuli. It is currently unknown, however, whether and how other neck muscles respond to vestibular stimuli. Here we measured activity bilaterally in the sternocleidomastoid, splenius capitis, sternohyoid, semispinalis capitis, multifidus, rectus capitis posterior, and obliquus capitis inferior using indwelling electrodes in two subjects exposed to binaural bipolar electrical vestibular stimuli. All recorded neck muscles responded to the electrical vestibular stimuli (0–100 Hz) provided they were active. Furthermore, the evoked responses were inverted on either side of the neck, consistent with a coordinated contribution of all left-right muscle pairs acting as antagonists in response to the electrically-evoked vestibular error of head motion. Overall, our results suggest that, as previously observed in cat neck muscles, broad connections exist between the human vestibular system and neck motoneurons and highlight the need for future investigations to establish their neural connections. |
| first_indexed | 2024-04-14T00:59:06Z |
| format | Article |
| id | doaj.art-392f4f8dd3034d58b1fa6075bc367e8f |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-14T00:59:06Z |
| publishDate | 2018-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-392f4f8dd3034d58b1fa6075bc367e8f2022-12-22T02:21:27ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-07-01910.3389/fneur.2018.00535387135Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in HumansPatrick A. Forbes0Patrick A. Forbes1Jason B. Fice2Gunter P. Siegmund3Gunter P. Siegmund4Jean-Sébastien Blouin5Jean-Sébastien Blouin6Jean-Sébastien Blouin7Department of Neuroscience, Erasmus Medical Centre, Rotterdam, NetherlandsDepartment of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering, Delft University of Technology, Delft, NetherlandsSchool of Kinesiology, University of British Columbia, Vancouver, BC, CanadaSchool of Kinesiology, University of British Columbia, Vancouver, BC, CanadaMEA Forensic Engineers & Scientists, Richmond, BC, CanadaSchool of Kinesiology, University of British Columbia, Vancouver, BC, CanadaDjavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, CanadaInstitute for Computing, Information and Cognitive Systems, University of British Columbia, Vancouver, BC, CanadaNeck muscle activity evoked by vestibular stimuli is a clinical measure for evaluating the function of the vestibular apparatus. Cervical vestibular-evoked myogenic potentials (cVEMP) are most commonly measured in the sternocleidomastoid muscle (and more recently the splenius capitis muscle) in response to air-conducted sound, bone-conducted vibration or electrical vestibular stimuli. It is currently unknown, however, whether and how other neck muscles respond to vestibular stimuli. Here we measured activity bilaterally in the sternocleidomastoid, splenius capitis, sternohyoid, semispinalis capitis, multifidus, rectus capitis posterior, and obliquus capitis inferior using indwelling electrodes in two subjects exposed to binaural bipolar electrical vestibular stimuli. All recorded neck muscles responded to the electrical vestibular stimuli (0–100 Hz) provided they were active. Furthermore, the evoked responses were inverted on either side of the neck, consistent with a coordinated contribution of all left-right muscle pairs acting as antagonists in response to the electrically-evoked vestibular error of head motion. Overall, our results suggest that, as previously observed in cat neck muscles, broad connections exist between the human vestibular system and neck motoneurons and highlight the need for future investigations to establish their neural connections.https://www.frontiersin.org/article/10.3389/fneur.2018.00535/fullcervical vestibular-evoked myogenic potentialsdeep and superficial neck muscleselectrical vestibular stimulationvestibulocollic pathwaysisometric neck muscle contractions |
| spellingShingle | Patrick A. Forbes Patrick A. Forbes Jason B. Fice Gunter P. Siegmund Gunter P. Siegmund Jean-Sébastien Blouin Jean-Sébastien Blouin Jean-Sébastien Blouin Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans Frontiers in Neurology cervical vestibular-evoked myogenic potentials deep and superficial neck muscles electrical vestibular stimulation vestibulocollic pathways isometric neck muscle contractions |
| title | Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans |
| title_full | Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans |
| title_fullStr | Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans |
| title_full_unstemmed | Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans |
| title_short | Electrical Vestibular Stimuli Evoke Robust Muscle Activity in Deep and Superficial Neck Muscles in Humans |
| title_sort | electrical vestibular stimuli evoke robust muscle activity in deep and superficial neck muscles in humans |
| topic | cervical vestibular-evoked myogenic potentials deep and superficial neck muscles electrical vestibular stimulation vestibulocollic pathways isometric neck muscle contractions |
| url | https://www.frontiersin.org/article/10.3389/fneur.2018.00535/full |
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