Synthesis and antitumor activity of certain 2,3,6-trisubstituted quinazolin-4(3H)-one derivatives
The synthesis of different series of 6-iodo-2-phenoxymethyl 3-substituted quinazolin-4(3H)-ones 5–17 is described. The structures of the newly synthesized compounds have been confirmed on the basis of elemental analyses, IR, 1H NMR and mass spectral data. Preliminary testing for the in vitro antitum...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Faculty of Pharmacy, Cairo University
2013-12-01
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Series: | Bulletin of Faculty of Pharmacy Cairo University |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1110093113000355 |