Synthesis and antitumor activity of certain 2,3,6-trisubstituted quinazolin-4(3H)-one derivatives

Synthesis and antitumor activity of certain 2,3,6-trisubstituted quinazolin-4(3H)-one derivatives

The synthesis of different series of 6-iodo-2-phenoxymethyl 3-substituted quinazolin-4(3H)-ones 5–17 is described. The structures of the newly synthesized compounds have been confirmed on the basis of elemental analyses, IR, 1H NMR and mass spectral data. Preliminary testing for the in vitro antitum...

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Bibliographic Details
Main Authors:	Safinaz E. Abbas, Flora F. Barsoum, Hanan H. Georgey, Eman R. Mohammed
Format:	Article
Language:	English
Published:	Faculty of Pharmacy, Cairo University 2013-12-01
Series:	Bulletin of Faculty of Pharmacy Cairo University
Subjects:	3-Amino-6-iodo-2-(phenoxymethyl)quinazolin-4(3H)-one 3-Chloroacetylamino derivative Antitumor activity
Online Access:	http://www.sciencedirect.com/science/article/pii/S1110093113000355

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