Lupus and recurrent pregnancy loss: the role of female sex hormones and B cells

Lupus and recurrent pregnancy loss: the role of female sex hormones and B cells

Systemic lupus erythematosus is a debilitating autoimmune disease characterized by uncontrolled activation of adaptive immunity, particularly B cells, which predominantly affects women in a 9 to 1 ratio compared to men. This stark sex disparity strongly suggests a role for female sex hormones in the...

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Bibliographic Details
Main Authors: Natalin Jimena Valeff, Maria Silvia Ventimiglia, Lianghui Diao, Federico Jensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
recurrent pregnancy loss
lupus
B cells
hormones
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1233883/full

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