A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies.
A promising direction in drug development is to exploit the ability of natural killer cells to kill antibody-labeled target cells. Monoclonal antibodies and drugs designed to elicit this effect typically bind cell-surface epitopes that are overexpressed on target cells but also present on other cell...
Main Authors: | Ryan N Gutenkunst, Daniel Coombs, Toby Starr, Michael L Dustin, Byron Goldstein |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3100730?pdf=render |
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