Comparison of Policosanols via Incorporation into Reconstituted High-Density Lipoproteins: Cuban Policosanol (Raydel<sup>®</sup>) Exerts the Highest Antioxidant, Anti-Glycation, and Anti-Inflammatory Activity

Comparison of Policosanols via Incorporation into Reconstituted High-Density Lipoproteins: Cuban Policosanol (Raydel<sup>®</sup>) Exerts the Highest Antioxidant, Anti-Glycation, and Anti-Inflammatory Activity

Reconstituted high-density lipoproteins (rHDL) containing each policosanol from Cuba (Raydel<sup>®</sup>), China (Shaanxi Pioneer), and the United States (Lesstanol<sup>®</sup>) were synthesized to compare the physiological properties of policosanol depending on sources and o...

Full description

Bibliographic Details
Main Authors:	Kyung-Hyun Cho, Ji-Eun Kim, Hyo-Seon Nam, Dae-Jin Kang, Seung-Hee Baek
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Molecules
Subjects:	HDL high-density lipoproteins apolipoprotein A-I policosanol sugar cane wax alcohol zebrafish
Online Access:	https://www.mdpi.com/1420-3049/28/18/6715

Similar Items

Consumption of Policosanol (Raydel<sup>®</sup>) Improves Hepatic, Renal, and Reproductive Functions in Zebrafish: In Vivo Comparison Study among Cuban, Chinese, and American Policosanol
by: Kyung-Hyun Cho, et al.
Published: (2023-12-01)

Cuban Sugar Cane Wax Alcohol Exhibited Enhanced Antioxidant, Anti-Glycation and Anti-Inflammatory Activity in Reconstituted High-Density Lipoprotein (rHDL) with Improved Structural and Functional Correlations: Comparison of Various Policosanols
by: Kyung-Hyun Cho, et al.
Published: (2023-02-01)

Cuban Policosanol (Raydel<sup>®</sup>) Potently Protects the Liver, Ovary, and Testis with an Improvement in Dyslipidemia in Hyperlipidemic Zebrafish: A Comparative Study with Three Chinese Policosanols
by: Kyung-Hyun Cho, et al.
Published: (2023-09-01)

Cuban policosanol improves high-density lipoprotein cholesterol efflux capacity in healthy Japanese subjects
by: Yoshinari Uehara, et al.
Published: (2024-01-01)

Combination Therapy of Cuban Policosanol (Raydel<sup>®</sup>, 20 mg) and Intensive Exercise for 12 Weeks Resulted in Improvements in Obesity, Hypertension, and Dyslipidemia without a Decrease in Serum Coenzyme Q<sub>10</sub>: Enhancement of Lipoproteins Quality and Antioxidant Functionality in Obese Participants
by: Kyung-Hyun Cho, et al.
Published: (2024-01-01)

Acute toxicity and chromosomal aberration toxicity of insect wax and its policosanol
by: Jinju Ma, et al.
Published: (2022-03-01)

Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese
by: Kyung-Hyun Cho, et al.
Published: (2023-03-01)

Cuban policosanol: a natural compound for ischemic stroke treatment
by: Vivian Molina Cuevas, et al.
Published: (2024-02-01)

Long-Term Consumption of Cuban Policosanol Lowers Central and Brachial Blood Pressure and Improves Lipid Profile With Enhancement of Lipoprotein Properties in Healthy Korean Participants
by: Suk-Jeong Kim, et al.
Published: (2018-04-01)

Policosanols lose their lustre as cholesterol-lowering agents
by: Peter J.H. Jones, et al.
Published: (2009-04-01)

Protection of Liver Functions and Improvement of Kidney Functions by Twelve Weeks Consumption of Cuban Policosanol (Raydel<sup>®</sup>) with a Decrease of Glycated Hemoglobin and Blood Pressure from a Randomized, Placebo-Controlled, and Double-Blinded Study with Healthy and Middle-Aged Japanese Participants
by: Kyung-Hyun Cho, et al.
Published: (2023-06-01)

Modulatory effects of policosanol from insect wax on lipid metabolism in high-fat diet-fed rats
by: Xian Li, et al.
Published: (2023-11-01)

Effect of policosanol on cerebral ischemia in Mongolian gerbils
by: V. Molina, et al.
Published: (1999-10-01)

Policosanol: Extraction and biological functions
by: Junjun Shen, et al.
Published: (2019-06-01)

Protective effect of policosanol on atherosclerotic lesions in rabbits with exogenous hypercholesterolemia
by: Arruzazabala M.L., et al.
Published: (2000-01-01)

Therapeutic potential of policosanol in the concurrent management of dyslipidemia and non-alcoholic fatty liver disease
by: Mandeep K. Arora, et al.
Published: (2022-01-01)

Blood Pressure Lowering Effect of Cuban Policosanol is Accompanied by Improvement of Hepatic Inflammation, Lipoprotein Profile, and HDL Quality in Spontaneously Hypertensive Rats
by: Kyung-Hyun Cho, et al.
Published: (2018-05-01)

Improving Effect of the Policosanol from <i>Ericerus pela</i> Wax on Learning and Memory Impairment Caused by Scopolamine in Mice
by: Long Sun, et al.
Published: (2022-07-01)

A New Strategy for Consumption of Functional Lipids from <i>Ericerus pela</i> (Chavannes): Study on Microcapsules and Effervescent Tablets Containing Insect Wax–Derived Policosanol
by: Yiwen Liu, et al.
Published: (2023-09-01)

Policosanol Stimulates Osteoblast Differentiation via Adenosine Monophosphate-Activated Protein Kinase-Mediated Expression of Insulin-Induced Genes 1 and 2
by: Kyeong-Min Kim, et al.
Published: (2023-07-01)

Policosanol composition, antioxidant and anti-arthritic activities of milk thistle (Silybium marianum L.) oil at different seed maturity stages
by: Saoussem Harrabi, et al.
Published: (2018-04-01)

Comparison of Policosanol Profiles of the Sprouts of Wheat Mutant Lines and the Effect of Differential LED Lights on Selected Lines
by: Ah-Reum Han, et al.
Published: (2023-09-01)

Long-Term Treatment of Cuban Policosanol Attenuates Abnormal Oxidative Stress and Inflammatory Response via Amyloid Plaques Reduction in 5xFAD Mice
by: Jin-Ho Kim, et al.
Published: (2021-08-01)

In vitro Evaluation of the Calcification Inhibitory Properties of Policosanol, Genistein, and Vitamin D (Reduplaxin®) either Alone or in Combination
by: Carla Iacobini, et al.
Published: (2024-01-01)

Integrated Metagenomics and Metabolomics to Reveal the Effects of Policosanol on Modulating the Gut Microbiota and Lipid Metabolism in Hyperlipidemic C57BL/6 Mice
by: Zhenya Zhai, et al.
Published: (2021-10-01)

Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols, and Berberine) in Patients with Low-Moderate Risk Hypercholesterolemia: A Double-Blind, Placebo-Controlled Study
by: Stefano Gonnelli, MD, et al.
Published: (2015-12-01)

Copycat-policosanols versus genuine policosanol
by: Víctor L. González Canavaciolo, et al.
Published: (2007-12-01)

A 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Saccharum officinarum wax alcohols (Policosanol) on improvement of blood cholesterol
by: Ha-Rim Kim, et al.
Published: (2023-08-01)

Policosanol ameliorates renal inflammation and pyroptosis in hypercholesterolemic rabbits via modulation of HMGB1/PI3K/mTOR/NLRP3/Caspase-1 pathway
by: Gehad M. Elnagar, et al.
Published: (2022-10-01)

Comparative Analysis of Policosanols Related to Growth Times from the Seedlings of Various Korean Oat (<i>Avena sativa</i> L.) Cultivars and Screening for Adenosine 5′-Monophosphate-Activated Protein Kinase (AMPK) Activation
by: Han-Gyeol Lee, et al.
Published: (2022-07-01)

Recovery of sugar cane cuticular wax by mechanical separation and solvent extraction
by: Alberto García, et al.
Published: (2003-06-01)

Enhancement of Antioxidant and Anti-Glycation Properties of Beeswax Alcohol in Reconstituted High-Density Lipoprotein: Safeguarding against Carboxymethyllysine Toxicity in Zebrafish
by: Kyung-Hyun Cho, et al.
Published: (2023-12-01)

Recapsoma<sup>®</sup>: A Novel Mixture Based on Bergamot, Ipomoea Batatas, Policosanol Extracts and Liposomal Berberine for the Treatment of Hypercholesterolemia
by: Chiara Amante, et al.
Published: (2022-07-01)

Current and Emerging Reconstituted HDL-apoA-I and HDL-apoE Approaches to Treat Atherosclerosis
by: Eftaxia-Konstantina Valanti, et al.
Published: (2018-10-01)

Policosanol extraction from beeswax and improvement of the purity
by: Srisaipet Anakhaorn, et al.
Published: (2017-01-01)

Multiple functions of policosanol in elderly patients with dyslipidemia
by: Chunlin Li, et al.
Published: (2020-07-01)

Apolipoprotein E3-mediated cellular uptake of reconstituted high-density lipoprotein bearing core 3, 10, or 17 nm hydrophobic gold nanoparticles
by: Chuang ST, et al.
Published: (2017-11-01)

Effect of Cuban Sugarcane Wax Acids and Policosanol on Serum Lipid Profile and Apolipoprotein A-I Expression in Hyperlipidemic Zebrafish
by: Kyung-Hyun Cho, et al.
Published: (2019-06-01)

Characterization of rice bran wax policosanol and its nanoemulsion formulation
by: Ishaka, Aminu, et al.
Published: (2014)

Ability of reconstituted high density lipoproteins to inhibit cytokine-induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells
by: Paul W. Baker, et al.
Published: (1999-02-01)