Hepatic artery disorders associated with alcoholism
Objective We aimed to characterize the relationship between severe chronic alcoholism and hepatic arterial wall disorders in humans. Methods We obtained hepatic arteries from 165 patients undergoing liver transplantation who were placed into two etiological groups: an Alcoholism group and a Non-alco...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-02-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605231153547 |
| _version_ | 1811169782566748160 |
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| author | Andy Petroianu Cecília Maria de Sousa Lagares Dabien Haddad Gisele Araújo Pereira Paula Vieira Teixeira Vidigal |
| author_facet | Andy Petroianu Cecília Maria de Sousa Lagares Dabien Haddad Gisele Araújo Pereira Paula Vieira Teixeira Vidigal |
| author_sort | Andy Petroianu |
| collection | DOAJ |
| description | Objective We aimed to characterize the relationship between severe chronic alcoholism and hepatic arterial wall disorders in humans. Methods We obtained hepatic arteries from 165 patients undergoing liver transplantation who were placed into two etiological groups: an Alcoholism group and a Non-alcoholism group. We compared the age, sex, lipid profile, and histologic characteristics of the hepatic arteries (normal, reduction in luminal diameter of ≤10%, or atherosclerosis) of the participants in the two groups using multifactor analyses. Results The Alcoholism group comprised 58 men and 40 women and the Non-alcoholism group comprised 63 men and 4 women. The mean ages of the groups were 52.5 ± 9.6 years and 44.2 ± 13.8 years, respectively. There were no circulating lipid abnormalities in any of the participants. In women, arterial disorders were found at a younger age than in men. Hepatic arterial disorders were more frequent in the non-alcoholic participants, and women with alcoholism showed less arterial narrowing. Conclusion The heavy consumption of alcoholic beverages is associated with a lower incidence of atherosclerosis of the hepatic artery in humans. |
| first_indexed | 2024-04-10T16:47:26Z |
| format | Article |
| id | doaj.art-393a4cf0bc5c4806bbd83208c1058f3f |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-04-10T16:47:26Z |
| publishDate | 2023-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-393a4cf0bc5c4806bbd83208c1058f3f2023-02-07T18:04:26ZengSAGE PublishingJournal of International Medical Research1473-23002023-02-015110.1177/03000605231153547Hepatic artery disorders associated with alcoholismAndy PetroianuCecília Maria de Sousa Lagares Dabien HaddadGisele Araújo PereiraPaula Vieira Teixeira VidigalObjective We aimed to characterize the relationship between severe chronic alcoholism and hepatic arterial wall disorders in humans. Methods We obtained hepatic arteries from 165 patients undergoing liver transplantation who were placed into two etiological groups: an Alcoholism group and a Non-alcoholism group. We compared the age, sex, lipid profile, and histologic characteristics of the hepatic arteries (normal, reduction in luminal diameter of ≤10%, or atherosclerosis) of the participants in the two groups using multifactor analyses. Results The Alcoholism group comprised 58 men and 40 women and the Non-alcoholism group comprised 63 men and 4 women. The mean ages of the groups were 52.5 ± 9.6 years and 44.2 ± 13.8 years, respectively. There were no circulating lipid abnormalities in any of the participants. In women, arterial disorders were found at a younger age than in men. Hepatic arterial disorders were more frequent in the non-alcoholic participants, and women with alcoholism showed less arterial narrowing. Conclusion The heavy consumption of alcoholic beverages is associated with a lower incidence of atherosclerosis of the hepatic artery in humans.https://doi.org/10.1177/03000605231153547 |
| spellingShingle | Andy Petroianu Cecília Maria de Sousa Lagares Dabien Haddad Gisele Araújo Pereira Paula Vieira Teixeira Vidigal Hepatic artery disorders associated with alcoholism Journal of International Medical Research |
| title | Hepatic artery disorders associated with alcoholism |
| title_full | Hepatic artery disorders associated with alcoholism |
| title_fullStr | Hepatic artery disorders associated with alcoholism |
| title_full_unstemmed | Hepatic artery disorders associated with alcoholism |
| title_short | Hepatic artery disorders associated with alcoholism |
| title_sort | hepatic artery disorders associated with alcoholism |
| url | https://doi.org/10.1177/03000605231153547 |
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