Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention

The prognostic value of exercise stress test after complex left main (LM) coronary artery bifurcation (LM) stenting has been poorly investigated. To partially fill this gap in knowledge, we retrospectively analyzed the procedural and medical data of consecutive patients referred to our center for co...

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Main Authors: Gianluca Rigatelli, Marco Zuin, Giuseppe Marchese, Ervis Hiso, Giulio Rodinò, Loris Roncon, Giampaolo Pasquetto
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/14/1/59
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author Gianluca Rigatelli
Marco Zuin
Giuseppe Marchese
Ervis Hiso
Giulio Rodinò
Loris Roncon
Giampaolo Pasquetto
author_facet Gianluca Rigatelli
Marco Zuin
Giuseppe Marchese
Ervis Hiso
Giulio Rodinò
Loris Roncon
Giampaolo Pasquetto
author_sort Gianluca Rigatelli
collection DOAJ
description The prognostic value of exercise stress test after complex left main (LM) coronary artery bifurcation (LM) stenting has been poorly investigated. To partially fill this gap in knowledge, we retrospectively analyzed the procedural and medical data of consecutive patients referred to our center for complex LM bifurcation disease between January 2008 and May 2018 who were treated using either single- or dual-stenting techniques. The prognostic impact of an exercise stress test, performed 6 months after the coronary intervention, was evaluated in 502 patients (316 males, mean age 70.3 ± 12.8 years, mean Syntax score 31.6 ± 6.3). At follow up after a mean of 37.1 ± 10.8 months (range 22.1–47.3 months), the target lesion failure (TLF) rate was 10.1% while stent thrombosis and cardiovascular mortality were 1.2 and 3.6%, respectively. A positive exercise stress test was detected at 6-month follow up in 42 out of 502 patients (8.4%); the incidence of a significant restenosis was 7.6% (<i>n</i> = 38). Patients with a negative exercise stress test at 6-month follow up had higher freedom from TLF and improved survival compared to those with a positive exercise stress test.
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spelling doaj.art-393ab91676654d1d81ae12c887ef6c432024-01-10T14:53:49ZengMDPI AGDiagnostics2075-44182023-12-011415910.3390/diagnostics14010059Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous InterventionGianluca Rigatelli0Marco Zuin1Giuseppe Marchese2Ervis Hiso3Giulio Rodinò4Loris Roncon5Giampaolo Pasquetto6Interventional Cardiology Unit, Division of Cardiology, Aulss6 Ospedali Riuniti Padova Sud, 35043 Monselice, ItalyDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, ItalyInterventional Cardiology Unit, Division of Cardiology, Aulss6 Ospedali Riuniti Padova Sud, 35043 Monselice, ItalyInterventional Cardiology Unit, Division of Cardiology, Aulss6 Ospedali Riuniti Padova Sud, 35043 Monselice, ItalyInterventional Cardiology Unit, Division of Cardiology, Aulss6 Ospedali Riuniti Padova Sud, 35043 Monselice, ItalyDepartment of Specialistic Medicine, Division of Cardiology, Rovigo General Hospital, 45100 Rovigo, ItalyInterventional Cardiology Unit, Division of Cardiology, Aulss6 Ospedali Riuniti Padova Sud, 35043 Monselice, ItalyThe prognostic value of exercise stress test after complex left main (LM) coronary artery bifurcation (LM) stenting has been poorly investigated. To partially fill this gap in knowledge, we retrospectively analyzed the procedural and medical data of consecutive patients referred to our center for complex LM bifurcation disease between January 2008 and May 2018 who were treated using either single- or dual-stenting techniques. The prognostic impact of an exercise stress test, performed 6 months after the coronary intervention, was evaluated in 502 patients (316 males, mean age 70.3 ± 12.8 years, mean Syntax score 31.6 ± 6.3). At follow up after a mean of 37.1 ± 10.8 months (range 22.1–47.3 months), the target lesion failure (TLF) rate was 10.1% while stent thrombosis and cardiovascular mortality were 1.2 and 3.6%, respectively. A positive exercise stress test was detected at 6-month follow up in 42 out of 502 patients (8.4%); the incidence of a significant restenosis was 7.6% (<i>n</i> = 38). Patients with a negative exercise stress test at 6-month follow up had higher freedom from TLF and improved survival compared to those with a positive exercise stress test.https://www.mdpi.com/2075-4418/14/1/59stentleft main bifurcationexercise stress test
spellingShingle Gianluca Rigatelli
Marco Zuin
Giuseppe Marchese
Ervis Hiso
Giulio Rodinò
Loris Roncon
Giampaolo Pasquetto
Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention
Diagnostics
stent
left main bifurcation
exercise stress test
title Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention
title_full Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention
title_fullStr Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention
title_full_unstemmed Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention
title_short Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention
title_sort prognostic impact of a routine six month exercise stress test after complex left main bifurcation percutaneous intervention
topic stent
left main bifurcation
exercise stress test
url https://www.mdpi.com/2075-4418/14/1/59
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