Radiation therapy for primary central nervous system lymphoma
Up until the late 1970s, radiation therapy played an important role in the treatment of primary central nervous system lymphoma (PCNSL) but more recently its role has changed due to the increased use of systemic chemotherapy. In this article, the current status of radiotherapy for PCNSL and optimal...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-09-01
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| Series: | Oncology Reviews |
| Subjects: | |
| Online Access: | http://www.oncologyreviews.org/index.php/or/article/view/229 |
| _version_ | 1797964733815455744 |
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| author | Yuta Shibamoto |
| author_facet | Yuta Shibamoto |
| author_sort | Yuta Shibamoto |
| collection | DOAJ |
| description | Up until the late 1970s, radiation therapy played an important role in the treatment of primary central nervous system lymphoma (PCNSL) but more recently its role has changed due to the increased use of systemic chemotherapy. In this article, the current status of radiotherapy for PCNSL and optimal forms of radiotherapy, including the treatment volume and radiation dose, are discussed. Data from nationwide Japanese surveys of PCNSL patients treated with radiation therapy suggest that the prognosis of PCNSL patients improved during the 1990s, in part due to the use of high-dose methotrexate-containing chemotherapy. The prognosis of patients treated with radiation alone also improved. Radiotherapy still seems to play an important role in the attempt to cure this disease. |
| first_indexed | 2024-04-11T01:48:34Z |
| format | Article |
| id | doaj.art-393b30ee322448ca92c1482081b7f046 |
| institution | Directory Open Access Journal |
| issn | 1970-5557 1970-5565 |
| language | English |
| last_indexed | 2024-04-11T01:48:34Z |
| publishDate | 2013-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Oncology Reviews |
| spelling | doaj.art-393b30ee322448ca92c1482081b7f0462023-01-03T07:00:54ZengFrontiers Media S.A.Oncology Reviews1970-55571970-55652013-09-017110.4081/oncol.2013.e4183Radiation therapy for primary central nervous system lymphomaYuta Shibamoto0Department of Radiology, Nagoya City University Graduate School of Medical Sciences, NagoyaUp until the late 1970s, radiation therapy played an important role in the treatment of primary central nervous system lymphoma (PCNSL) but more recently its role has changed due to the increased use of systemic chemotherapy. In this article, the current status of radiotherapy for PCNSL and optimal forms of radiotherapy, including the treatment volume and radiation dose, are discussed. Data from nationwide Japanese surveys of PCNSL patients treated with radiation therapy suggest that the prognosis of PCNSL patients improved during the 1990s, in part due to the use of high-dose methotrexate-containing chemotherapy. The prognosis of patients treated with radiation alone also improved. Radiotherapy still seems to play an important role in the attempt to cure this disease.http://www.oncologyreviews.org/index.php/or/article/view/229brain neoplasmlymphomacentral nervous systemradiotherapychemotherapy. |
| spellingShingle | Yuta Shibamoto Radiation therapy for primary central nervous system lymphoma Oncology Reviews brain neoplasm lymphoma central nervous system radiotherapy chemotherapy. |
| title | Radiation therapy for primary central nervous system lymphoma |
| title_full | Radiation therapy for primary central nervous system lymphoma |
| title_fullStr | Radiation therapy for primary central nervous system lymphoma |
| title_full_unstemmed | Radiation therapy for primary central nervous system lymphoma |
| title_short | Radiation therapy for primary central nervous system lymphoma |
| title_sort | radiation therapy for primary central nervous system lymphoma |
| topic | brain neoplasm lymphoma central nervous system radiotherapy chemotherapy. |
| url | http://www.oncologyreviews.org/index.php/or/article/view/229 |
| work_keys_str_mv | AT yutashibamoto radiationtherapyforprimarycentralnervoussystemlymphoma |