Enamel surface remineralization: Using synthetic nanohydroxyapatite
Objective: The purpose of this study was to evaluate the effects of synthetically processed hydroxyapatite particles in remineralization of the early enamel lesions in comparison with 2% sodium fluoride. Materials and Methods: Thirty sound human premolars were divided into nanohydroxyapatite group (...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Contemporary Clinical Dentistry |
| Subjects: | |
| Online Access: | http://www.contempclindent.org/article.asp?issn=0976-237X;year=2012;volume=3;issue=4;spage=433;epage=436;aulast=Swarup |
| _version_ | 1818513957510447104 |
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| author | J Shanti Swarup Arathi Rao |
| author_facet | J Shanti Swarup Arathi Rao |
| author_sort | J Shanti Swarup |
| collection | DOAJ |
| description | Objective: The purpose of this study was to evaluate the effects of synthetically processed hydroxyapatite particles in remineralization of the early enamel lesions in comparison with 2% sodium fluoride. Materials and Methods: Thirty sound human premolars were divided into nanohydroxyapatite group (n0 = 15) and the sodium fluoride group (n = 15). The specimens were subjected to demineralization before being coated with 10% aqueous slurry of 20 nm nanohydroxyapatite or 2% sodium fluoride. The remineralizing efficacy of the materials was evaluated using surface microhardness (SMH) measurements, scanning microscopic analysis and analysis of the Ca/P ratio of the surface enamel. Data analysis was carried out using paired t-test and independent t-test. Results: The results showed that the nanohydroxyapatite group produced a surface morphology close to the biologic enamel, the increase in mineral content (Ca/P ratio) was more significant in the nanohydroxyapatite group ( P < 0.05) and the SMH recovery was closer to the baseline level in the nanohydroxyapatite group (P < 0.05). Both the groups did not show any significant difference in thickness (P > 0.05). Conclusion: The use of biomimetic nanohydroxyapatite as a remineralizing agent holds promise as a new synthetic enamel biocompatible material to repair early carious lesions. |
| first_indexed | 2024-12-11T00:08:42Z |
| format | Article |
| id | doaj.art-393ed00b71354e05941d65d2013fd33f |
| institution | Directory Open Access Journal |
| issn | 0976-237X 0976-2361 |
| language | English |
| last_indexed | 2024-12-11T00:08:42Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Contemporary Clinical Dentistry |
| spelling | doaj.art-393ed00b71354e05941d65d2013fd33f2022-12-22T01:28:13ZengWolters Kluwer Medknow PublicationsContemporary Clinical Dentistry0976-237X0976-23612012-01-013443343610.4103/0976-237X.107434Enamel surface remineralization: Using synthetic nanohydroxyapatiteJ Shanti SwarupArathi RaoObjective: The purpose of this study was to evaluate the effects of synthetically processed hydroxyapatite particles in remineralization of the early enamel lesions in comparison with 2% sodium fluoride. Materials and Methods: Thirty sound human premolars were divided into nanohydroxyapatite group (n0 = 15) and the sodium fluoride group (n = 15). The specimens were subjected to demineralization before being coated with 10% aqueous slurry of 20 nm nanohydroxyapatite or 2% sodium fluoride. The remineralizing efficacy of the materials was evaluated using surface microhardness (SMH) measurements, scanning microscopic analysis and analysis of the Ca/P ratio of the surface enamel. Data analysis was carried out using paired t-test and independent t-test. Results: The results showed that the nanohydroxyapatite group produced a surface morphology close to the biologic enamel, the increase in mineral content (Ca/P ratio) was more significant in the nanohydroxyapatite group ( P < 0.05) and the SMH recovery was closer to the baseline level in the nanohydroxyapatite group (P < 0.05). Both the groups did not show any significant difference in thickness (P > 0.05). Conclusion: The use of biomimetic nanohydroxyapatite as a remineralizing agent holds promise as a new synthetic enamel biocompatible material to repair early carious lesions.http://www.contempclindent.org/article.asp?issn=0976-237X;year=2012;volume=3;issue=4;spage=433;epage=436;aulast=SwarupBiomimeticenamelmicrohardnessmineral contentnanohydroxyapatiteremineralizationsodium fluoride |
| spellingShingle | J Shanti Swarup Arathi Rao Enamel surface remineralization: Using synthetic nanohydroxyapatite Contemporary Clinical Dentistry Biomimetic enamel microhardness mineral content nanohydroxyapatite remineralization sodium fluoride |
| title | Enamel surface remineralization: Using synthetic nanohydroxyapatite |
| title_full | Enamel surface remineralization: Using synthetic nanohydroxyapatite |
| title_fullStr | Enamel surface remineralization: Using synthetic nanohydroxyapatite |
| title_full_unstemmed | Enamel surface remineralization: Using synthetic nanohydroxyapatite |
| title_short | Enamel surface remineralization: Using synthetic nanohydroxyapatite |
| title_sort | enamel surface remineralization using synthetic nanohydroxyapatite |
| topic | Biomimetic enamel microhardness mineral content nanohydroxyapatite remineralization sodium fluoride |
| url | http://www.contempclindent.org/article.asp?issn=0976-237X;year=2012;volume=3;issue=4;spage=433;epage=436;aulast=Swarup |
| work_keys_str_mv | AT jshantiswarup enamelsurfaceremineralizationusingsyntheticnanohydroxyapatite AT arathirao enamelsurfaceremineralizationusingsyntheticnanohydroxyapatite |