Annexin V–CLIO: A Nanoparticle for Detecting Apoptosis by MRI

Annexin V–CLIO: A Nanoparticle for Detecting Apoptosis by MRI

Annexin V, which recognizes the phosphatidylserine of apoptotic cells, was conjugated to crosslinked iron oxide (CLIO) nanoparticles, a functionalized superparamagnetic preparation developed for target-specific magnetic resonance imaging (MRI). The resulting nanoparticle had an average of 2.7 annexi...

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Bibliographic Details
Main Authors: Eyk A. Schellenberger, Alexei Bogdanov, Dagmar Högemann, Jonathan Tait, Ralph Weissleder, Lee Josephson
Format: Article
Language:English
Published: SAGE Publications 2002-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200202103

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