Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2012-01-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/18/1/11-1092_article |
| _version_ | 1818133636161994752 |
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| author | Nadine Mestre-Francés Simon Nicot Sylvie Rouland Anne-Gaëlle Biacabe Isabelle Quadrio Armand Perret-Liaudet Thierry Baron Jean-Michel Verdier |
| author_facet | Nadine Mestre-Francés Simon Nicot Sylvie Rouland Anne-Gaëlle Biacabe Isabelle Quadrio Armand Perret-Liaudet Thierry Baron Jean-Michel Verdier |
| author_sort | Nadine Mestre-Francés |
| collection | DOAJ |
| description | We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue. |
| first_indexed | 2024-12-11T08:55:52Z |
| format | Article |
| id | doaj.art-39442fd73fd14292a15a5d8d9924a85a |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-11T08:55:52Z |
| publishDate | 2012-01-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-39442fd73fd14292a15a5d8d9924a85a2022-12-22T01:13:54ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592012-01-0118114214510.3201/eid1801.111092Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate ModelNadine Mestre-FrancésSimon NicotSylvie RoulandAnne-Gaëlle BiacabeIsabelle QuadrioArmand Perret-LiaudetThierry BaronJean-Michel VerdierWe report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.https://wwwnc.cdc.gov/eid/article/18/1/11-1092_articleprionprions and related diseasesbovine spongiform encephalopathyBSEL-type BSEmouse lemur |
| spellingShingle | Nadine Mestre-Francés Simon Nicot Sylvie Rouland Anne-Gaëlle Biacabe Isabelle Quadrio Armand Perret-Liaudet Thierry Baron Jean-Michel Verdier Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model Emerging Infectious Diseases prion prions and related diseases bovine spongiform encephalopathy BSE L-type BSE mouse lemur |
| title | Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model |
| title_full | Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model |
| title_fullStr | Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model |
| title_full_unstemmed | Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model |
| title_short | Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model |
| title_sort | oral transmission of l type bovine spongiform encephalopathy in primate model |
| topic | prion prions and related diseases bovine spongiform encephalopathy BSE L-type BSE mouse lemur |
| url | https://wwwnc.cdc.gov/eid/article/18/1/11-1092_article |
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