Herbal medicine and its impact on the gut microbiota in colorectal cancer
It is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With the development of sequencing technology and the application of germ-free models in recent years, significant inroads...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2023.1096008/full |
| _version_ | 1827908771066675200 |
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| author | Fan Bu Yifeng Tu Ziang Wan Shiliang Tu |
| author_facet | Fan Bu Yifeng Tu Ziang Wan Shiliang Tu |
| author_sort | Fan Bu |
| collection | DOAJ |
| description | It is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With the development of sequencing technology and the application of germ-free models in recent years, significant inroads have been achieved in research on GM and microbiota-related metabolites. Accordingly, the role and mechanism of GM in colorectal cancer (CRC) development have been gradually revealed. Traditional Chinese medicine (TCM) represents an important source of natural medicines and herbal products, with huge potential as anti-CRC agents. The potential application of TCM to target gut microbes for the treatment of colorectal cancer represents an exciting area of investigation. |
| first_indexed | 2024-03-13T01:26:58Z |
| format | Article |
| id | doaj.art-394902b238904df592bd0c47f81c4902 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-03-13T01:26:58Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-394902b238904df592bd0c47f81c49022023-07-04T12:28:56ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882023-07-011310.3389/fcimb.2023.10960081096008Herbal medicine and its impact on the gut microbiota in colorectal cancerFan Bu0Yifeng Tu1Ziang Wan2Shiliang Tu3Department of Colorectal Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, ChinaThe Second Affiliated College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaDepartment of Colorectal Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, ChinaDepartment of Colorectal Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, ChinaIt is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With the development of sequencing technology and the application of germ-free models in recent years, significant inroads have been achieved in research on GM and microbiota-related metabolites. Accordingly, the role and mechanism of GM in colorectal cancer (CRC) development have been gradually revealed. Traditional Chinese medicine (TCM) represents an important source of natural medicines and herbal products, with huge potential as anti-CRC agents. The potential application of TCM to target gut microbes for the treatment of colorectal cancer represents an exciting area of investigation.https://www.frontiersin.org/articles/10.3389/fcimb.2023.1096008/fullmicrobial metabolismgut microbiotaherbal medicinecolorectal cancerbile acids |
| spellingShingle | Fan Bu Yifeng Tu Ziang Wan Shiliang Tu Herbal medicine and its impact on the gut microbiota in colorectal cancer Frontiers in Cellular and Infection Microbiology microbial metabolism gut microbiota herbal medicine colorectal cancer bile acids |
| title | Herbal medicine and its impact on the gut microbiota in colorectal cancer |
| title_full | Herbal medicine and its impact on the gut microbiota in colorectal cancer |
| title_fullStr | Herbal medicine and its impact on the gut microbiota in colorectal cancer |
| title_full_unstemmed | Herbal medicine and its impact on the gut microbiota in colorectal cancer |
| title_short | Herbal medicine and its impact on the gut microbiota in colorectal cancer |
| title_sort | herbal medicine and its impact on the gut microbiota in colorectal cancer |
| topic | microbial metabolism gut microbiota herbal medicine colorectal cancer bile acids |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2023.1096008/full |
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