Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin

Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin

Increased levels and diversity of human endogenous retrovirus (HERV) transcription characterize most cancer types and are linked with disease outcomes. However, the underlying processes are incompletely understood. Here, we show that elevated transcription of HERVH proviruses predicted survival of l...

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Bibliographic Details
Main Authors: Jan Attig, Judith Pape, Laura Doglio, Anastasiya Kazachenka, Eleonora Ottina, George R. Young, Katey S.S. Enfield, Iker Valle Aramburu, Kevin W. Ng, Nikhil Faulkner, William Bolland, Venizelos Papayannopoulos, Charles Swanton, George Kassiotis
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-07-01
Series:The Journal of Clinical Investigation
Subjects:
Genetics
Oncology
Online Access:https://doi.org/10.1172/JCI164397

Internet

https://doi.org/10.1172/JCI164397

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