Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane
The experiment assessed the cardiorespiratory and hemogasometric profiles in female cats under sevoflurane resulting from the administration of tramadol. Twenty clinically healthy adult female cats separated equally into two groups: control group (CG) and tramadol group (TG) were sedated with intra...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Uberlândia
2016-06-01
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| Series: | Bioscience Journal |
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| Online Access: | https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/29890 |
| _version_ | 1818287867707785216 |
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| author | Moacir Santos de Lacerda Renato Linhares Sampaio Rodrigo Supranzetti de Rezende Thiago Cunha Nunes |
| author_facet | Moacir Santos de Lacerda Renato Linhares Sampaio Rodrigo Supranzetti de Rezende Thiago Cunha Nunes |
| author_sort | Moacir Santos de Lacerda |
| collection | DOAJ |
| description |
The experiment assessed the cardiorespiratory and hemogasometric profiles in female cats under sevoflurane resulting from the administration of tramadol. Twenty clinically healthy adult female cats separated equally into two groups: control group (CG) and tramadol group (TG) were sedated with intramuscular acepromazine (0.05 mg/kg), followed by anesthetic induction intravenous propofol (5mg/kg). After endotracheal intubation, animals were maintained on sevoflurane in oxygen administered using a non-rebreathing (Baraka) circuit. The oxygen flow-rate was maintained at 2 L per minute. Fifteen minutes after induction, either 0.05 ml/kg 0.9% saline solution or 2mg/kg tramadol were administered, both intramuscularly, to the animals in CG and TG, respectively. The period of time immediately previous to these administrations was considered as moment zero (T0). The variables were again measured 15 minutes later (T15) and subsequently in 15 minute intervals for a total of sixty minutes (T30, T45 and T60). The results were statistically evaluated through variance analysis of repeated measures (ANOVA) followed by a Tukey test or Student t-test with the nullity hypothesis rejection level set to p<0.05. The use of tramadol reduced cardiac frequency (CF), systolic arterial pressure (SAP), diastolic arterial pressure (DAP) and mean arterial pressure (MAP). There was a reduction of the respiratory frequency (RF) and an elevation of the PaCO2. The body temperature (ºC) lowered in both groups throughout the experiment. The results allow us to conclude that tramadol in cats anesthetized with sevoflurane does not undergo significant cardiorespiratory and blood-gas changes, although there are significant differences in some parameters between groups, all results remained within feline standard physiological values.
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| first_indexed | 2024-12-13T01:47:19Z |
| format | Article |
| id | doaj.art-394bc9ffaab24330b45577637f4aeaf1 |
| institution | Directory Open Access Journal |
| issn | 1981-3163 |
| language | English |
| last_indexed | 2024-12-13T01:47:19Z |
| publishDate | 2016-06-01 |
| publisher | Universidade Federal de Uberlândia |
| record_format | Article |
| series | Bioscience Journal |
| spelling | doaj.art-394bc9ffaab24330b45577637f4aeaf12022-12-22T00:03:36ZengUniversidade Federal de UberlândiaBioscience Journal1981-31632016-06-01323Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane Moacir Santos de Lacerda0Renato Linhares SampaioRodrigo Supranzetti de RezendeThiago Cunha NunesUBERABA OF UNIVERSITY The experiment assessed the cardiorespiratory and hemogasometric profiles in female cats under sevoflurane resulting from the administration of tramadol. Twenty clinically healthy adult female cats separated equally into two groups: control group (CG) and tramadol group (TG) were sedated with intramuscular acepromazine (0.05 mg/kg), followed by anesthetic induction intravenous propofol (5mg/kg). After endotracheal intubation, animals were maintained on sevoflurane in oxygen administered using a non-rebreathing (Baraka) circuit. The oxygen flow-rate was maintained at 2 L per minute. Fifteen minutes after induction, either 0.05 ml/kg 0.9% saline solution or 2mg/kg tramadol were administered, both intramuscularly, to the animals in CG and TG, respectively. The period of time immediately previous to these administrations was considered as moment zero (T0). The variables were again measured 15 minutes later (T15) and subsequently in 15 minute intervals for a total of sixty minutes (T30, T45 and T60). The results were statistically evaluated through variance analysis of repeated measures (ANOVA) followed by a Tukey test or Student t-test with the nullity hypothesis rejection level set to p<0.05. The use of tramadol reduced cardiac frequency (CF), systolic arterial pressure (SAP), diastolic arterial pressure (DAP) and mean arterial pressure (MAP). There was a reduction of the respiratory frequency (RF) and an elevation of the PaCO2. The body temperature (ºC) lowered in both groups throughout the experiment. The results allow us to conclude that tramadol in cats anesthetized with sevoflurane does not undergo significant cardiorespiratory and blood-gas changes, although there are significant differences in some parameters between groups, all results remained within feline standard physiological values. https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/29890Felis catusOpioidsAnesthesia |
| spellingShingle | Moacir Santos de Lacerda Renato Linhares Sampaio Rodrigo Supranzetti de Rezende Thiago Cunha Nunes Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane Bioscience Journal Felis catus Opioids Anesthesia |
| title | Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane |
| title_full | Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane |
| title_fullStr | Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane |
| title_full_unstemmed | Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane |
| title_short | Cardiopulmonary and acid-base effects of tramadol in cats anesthetized with sevoflurane |
| title_sort | cardiopulmonary and acid base effects of tramadol in cats anesthetized with sevoflurane |
| topic | Felis catus Opioids Anesthesia |
| url | https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/29890 |
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