Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
In the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colonisation on textiles. The adopted methodology incl...
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MDPI AG
2024-03-01
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Series: | Molecules |
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Online Access: | https://www.mdpi.com/1420-3049/29/6/1209 |
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author | Resmarani Sahu Neethu Ninan Ngoc Huu Nguyen Jianzhong Wang Krasimir Vasilev Vi Khanh Truong Youhong Tang |
author_facet | Resmarani Sahu Neethu Ninan Ngoc Huu Nguyen Jianzhong Wang Krasimir Vasilev Vi Khanh Truong Youhong Tang |
author_sort | Resmarani Sahu |
collection | DOAJ |
description | In the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colonisation on textiles. The adopted methodology includes a multi-step process using plasma polymerisation and subsequent integration of AIE PS on their surface. The antibacterial effectiveness of the coating was tested against <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i> after light irradiation for 1 h. Furthermore, antibacterial mechanistic studies revealed their ability to generate reactive oxygen species that can damage bacterial cell membrane integrity. The results of this investigation can be used to develop ground-breaking explanations for infection deterrence, principally in situations where hospital fabrics play a critical part in the transmission of diseases. The antibacterial coating for textiles developed in this study holds great promise as an efficient strategy to promote public health and reduce the danger of bacterial diseases through regular contact with fabrics. |
first_indexed | 2024-04-24T17:58:06Z |
format | Article |
id | doaj.art-394d62f2859546b69dd8eb9e2a606a0f |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-04-24T17:58:06Z |
publishDate | 2024-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-394d62f2859546b69dd8eb9e2a606a0f2024-03-27T13:56:44ZengMDPI AGMolecules1420-30492024-03-01296120910.3390/molecules29061209Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated InfectionsResmarani Sahu0Neethu Ninan1Ngoc Huu Nguyen2Jianzhong Wang3Krasimir Vasilev4Vi Khanh Truong5Youhong Tang6College of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaInstitute for NanoScale Science and Technology, Medical Device Research Institute, College of Science and Engineering, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaInstitute for NanoScale Science and Technology, Medical Device Research Institute, College of Science and Engineering, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaIn the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colonisation on textiles. The adopted methodology includes a multi-step process using plasma polymerisation and subsequent integration of AIE PS on their surface. The antibacterial effectiveness of the coating was tested against <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i> after light irradiation for 1 h. Furthermore, antibacterial mechanistic studies revealed their ability to generate reactive oxygen species that can damage bacterial cell membrane integrity. The results of this investigation can be used to develop ground-breaking explanations for infection deterrence, principally in situations where hospital fabrics play a critical part in the transmission of diseases. The antibacterial coating for textiles developed in this study holds great promise as an efficient strategy to promote public health and reduce the danger of bacterial diseases through regular contact with fabrics.https://www.mdpi.com/1420-3049/29/6/1209aggregation-induced emission photosensitisershealthcare-associated infectionsplasma coatingantibacterialtextile |
spellingShingle | Resmarani Sahu Neethu Ninan Ngoc Huu Nguyen Jianzhong Wang Krasimir Vasilev Vi Khanh Truong Youhong Tang Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections Molecules aggregation-induced emission photosensitisers healthcare-associated infections plasma coating antibacterial textile |
title | Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections |
title_full | Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections |
title_fullStr | Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections |
title_full_unstemmed | Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections |
title_short | Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections |
title_sort | antibacterial textile coating armoured with aggregation induced emission photosensitisers to prevent healthcare associated infections |
topic | aggregation-induced emission photosensitisers healthcare-associated infections plasma coating antibacterial textile |
url | https://www.mdpi.com/1420-3049/29/6/1209 |
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