Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections

In the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colonisation on textiles. The adopted methodology incl...

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Main Authors: Resmarani Sahu, Neethu Ninan, Ngoc Huu Nguyen, Jianzhong Wang, Krasimir Vasilev, Vi Khanh Truong, Youhong Tang
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/6/1209
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author Resmarani Sahu
Neethu Ninan
Ngoc Huu Nguyen
Jianzhong Wang
Krasimir Vasilev
Vi Khanh Truong
Youhong Tang
author_facet Resmarani Sahu
Neethu Ninan
Ngoc Huu Nguyen
Jianzhong Wang
Krasimir Vasilev
Vi Khanh Truong
Youhong Tang
author_sort Resmarani Sahu
collection DOAJ
description In the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colonisation on textiles. The adopted methodology includes a multi-step process using plasma polymerisation and subsequent integration of AIE PS on their surface. The antibacterial effectiveness of the coating was tested against <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i> after light irradiation for 1 h. Furthermore, antibacterial mechanistic studies revealed their ability to generate reactive oxygen species that can damage bacterial cell membrane integrity. The results of this investigation can be used to develop ground-breaking explanations for infection deterrence, principally in situations where hospital fabrics play a critical part in the transmission of diseases. The antibacterial coating for textiles developed in this study holds great promise as an efficient strategy to promote public health and reduce the danger of bacterial diseases through regular contact with fabrics.
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spelling doaj.art-394d62f2859546b69dd8eb9e2a606a0f2024-03-27T13:56:44ZengMDPI AGMolecules1420-30492024-03-01296120910.3390/molecules29061209Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated InfectionsResmarani Sahu0Neethu Ninan1Ngoc Huu Nguyen2Jianzhong Wang3Krasimir Vasilev4Vi Khanh Truong5Youhong Tang6College of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaInstitute for NanoScale Science and Technology, Medical Device Research Institute, College of Science and Engineering, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaCollege of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaInstitute for NanoScale Science and Technology, Medical Device Research Institute, College of Science and Engineering, Flinders University, Bedford Park, Adelaide, SA 5042, AustraliaIn the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colonisation on textiles. The adopted methodology includes a multi-step process using plasma polymerisation and subsequent integration of AIE PS on their surface. The antibacterial effectiveness of the coating was tested against <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i> after light irradiation for 1 h. Furthermore, antibacterial mechanistic studies revealed their ability to generate reactive oxygen species that can damage bacterial cell membrane integrity. The results of this investigation can be used to develop ground-breaking explanations for infection deterrence, principally in situations where hospital fabrics play a critical part in the transmission of diseases. The antibacterial coating for textiles developed in this study holds great promise as an efficient strategy to promote public health and reduce the danger of bacterial diseases through regular contact with fabrics.https://www.mdpi.com/1420-3049/29/6/1209aggregation-induced emission photosensitisershealthcare-associated infectionsplasma coatingantibacterialtextile
spellingShingle Resmarani Sahu
Neethu Ninan
Ngoc Huu Nguyen
Jianzhong Wang
Krasimir Vasilev
Vi Khanh Truong
Youhong Tang
Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
Molecules
aggregation-induced emission photosensitisers
healthcare-associated infections
plasma coating
antibacterial
textile
title Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
title_full Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
title_fullStr Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
title_full_unstemmed Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
title_short Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections
title_sort antibacterial textile coating armoured with aggregation induced emission photosensitisers to prevent healthcare associated infections
topic aggregation-induced emission photosensitisers
healthcare-associated infections
plasma coating
antibacterial
textile
url https://www.mdpi.com/1420-3049/29/6/1209
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AT jianzhongwang antibacterialtextilecoatingarmouredwithaggregationinducedemissionphotosensitiserstopreventhealthcareassociatedinfections
AT krasimirvasilev antibacterialtextilecoatingarmouredwithaggregationinducedemissionphotosensitiserstopreventhealthcareassociatedinfections
AT vikhanhtruong antibacterialtextilecoatingarmouredwithaggregationinducedemissionphotosensitiserstopreventhealthcareassociatedinfections
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