Characterisation of δ-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator

Characterisation of δ-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator

The 27-amino acid (aa)-long δ-conotoxin TxVIA, originally isolated from the mollusc-hunting cone snail <i>Conus textile</i>, slows voltage-gated sodium (Na<sub>V</sub>) channel inactivation in molluscan neurons, but its mammalian ion channel targets remain undetermined. In th...

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Bibliographic Details
Main Authors:	Dan Wang, S.W.A. Himaya, Jean Giacomotto, Md. Mahadhi Hasan, Fernanda C. Cardoso, Lotten Ragnarsson, Richard J. Lewis
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Marine Drugs
Subjects:	TxVIA mammalian Na<sub>V</sub> channel selective inhibitor T-type Ca<sub>V</sub>3.2
Online Access:	https://www.mdpi.com/1660-3397/18/7/343

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