In situ Forming Systems for Wound Healing: A Review
In-situ forming systems are liquid or viscous injectable materials that after being injected into the body, due to mixing with reactive substances or in response to new conditions (temperature, pH, presence of special molecules or ions, visible or ultraviolet light radiation), they formed a semi-sol...
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| Format: | Article |
| Language: | fas |
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Iran Polymer & Petrochemical Institute
2022-11-01
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| Series: | Baspārish |
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| Online Access: | http://basparesh.ippi.ac.ir/article_1849_dca5aabfaa41603a5b203434834e159f.pdf |
| _version_ | 1811175389345611776 |
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| author | Sara Sara Janghorban-Laricheh Moslem Tavakol |
| author_facet | Sara Sara Janghorban-Laricheh Moslem Tavakol |
| author_sort | Sara Sara Janghorban-Laricheh |
| collection | DOAJ |
| description | In-situ forming systems are liquid or viscous injectable materials that after being injected into the body, due to mixing with reactive substances or in response to new conditions (temperature, pH, presence of special molecules or ions, visible or ultraviolet light radiation), they formed a semi-solid material or gel. In the recent years, due to the unique characteristics of in situ forming systems, preparation and investigation of these systems for wound healing have gained increasing attentions. In addition to easy and non-invasive injection of in situ forming systems, these materials can completely fill irregular wound defects and adhere to the wound edge tissues. Also these materials can simultaneously act as a controlled drug delivery system, cell carrier/tissue scaffold, hemostatic agent and tissue-adhesive. Until now, several physical, chemical and enzymatically cross-linking methods have been used to prepare in situ forming systems/hydrogels. In this review, various emerging and innovative approaches being developed and utilized for the preparation of in situ forming systems/hydrogels for wound dressing are reviewed. Also challenges and future prospects of these systems are discussed. |
| first_indexed | 2024-04-10T19:35:21Z |
| format | Article |
| id | doaj.art-395a0fcfac99411b9d083cd520e9a043 |
| institution | Directory Open Access Journal |
| issn | 2252-0449 2538-5445 |
| language | fas |
| last_indexed | 2024-04-10T19:35:21Z |
| publishDate | 2022-11-01 |
| publisher | Iran Polymer & Petrochemical Institute |
| record_format | Article |
| series | Baspārish |
| spelling | doaj.art-395a0fcfac99411b9d083cd520e9a0432023-01-30T06:16:05ZfasIran Polymer & Petrochemical InstituteBaspārish2252-04492538-54452022-11-01123304110.22063/basparesh.2021.2998.15851849In situ Forming Systems for Wound Healing: A ReviewSara Sara Janghorban-Laricheh0Moslem Tavakol1Department of Chemical & Polymer Engineering, Faculty of Engineering, Yazd University, Yazd, IranDepartment of Chemical & Polymer Engineering, Faculty of Engineering, Yazd University, Yazd, IranIn-situ forming systems are liquid or viscous injectable materials that after being injected into the body, due to mixing with reactive substances or in response to new conditions (temperature, pH, presence of special molecules or ions, visible or ultraviolet light radiation), they formed a semi-solid material or gel. In the recent years, due to the unique characteristics of in situ forming systems, preparation and investigation of these systems for wound healing have gained increasing attentions. In addition to easy and non-invasive injection of in situ forming systems, these materials can completely fill irregular wound defects and adhere to the wound edge tissues. Also these materials can simultaneously act as a controlled drug delivery system, cell carrier/tissue scaffold, hemostatic agent and tissue-adhesive. Until now, several physical, chemical and enzymatically cross-linking methods have been used to prepare in situ forming systems/hydrogels. In this review, various emerging and innovative approaches being developed and utilized for the preparation of in situ forming systems/hydrogels for wound dressing are reviewed. Also challenges and future prospects of these systems are discussed.http://basparesh.ippi.ac.ir/article_1849_dca5aabfaa41603a5b203434834e159f.pdfin situ forming systemcrosslinking methodwound healinghydrogelwound dressing |
| spellingShingle | Sara Sara Janghorban-Laricheh Moslem Tavakol In situ Forming Systems for Wound Healing: A Review Baspārish in situ forming system crosslinking method wound healing hydrogel wound dressing |
| title | In situ Forming Systems for Wound Healing: A Review |
| title_full | In situ Forming Systems for Wound Healing: A Review |
| title_fullStr | In situ Forming Systems for Wound Healing: A Review |
| title_full_unstemmed | In situ Forming Systems for Wound Healing: A Review |
| title_short | In situ Forming Systems for Wound Healing: A Review |
| title_sort | in situ forming systems for wound healing a review |
| topic | in situ forming system crosslinking method wound healing hydrogel wound dressing |
| url | http://basparesh.ippi.ac.ir/article_1849_dca5aabfaa41603a5b203434834e159f.pdf |
| work_keys_str_mv | AT sarasarajanghorbanlaricheh insituformingsystemsforwoundhealingareview AT moslemtavakol insituformingsystemsforwoundhealingareview |