Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy
(1) Background: Numerous studies have shown the beneficial role of fluoride in the primary prevention of dental caries. The aim of the present study was to put into evidence the change in the enamel structure immediately after the application of a fluoride varnish. (2) Methods: A xylitol–fluoride va...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
|
| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/10/8/1900 |
| _version_ | 1827600626727518208 |
|---|---|
| author | Catalina Iulia Saveanu Oana Dragos Daniela Anistoroaei Livia Ionela Bobu Alexandra Ecaterina Saveanu Adina Armencia Sorina Mihaela Solomon Oana Tanculescu |
| author_facet | Catalina Iulia Saveanu Oana Dragos Daniela Anistoroaei Livia Ionela Bobu Alexandra Ecaterina Saveanu Adina Armencia Sorina Mihaela Solomon Oana Tanculescu |
| author_sort | Catalina Iulia Saveanu |
| collection | DOAJ |
| description | (1) Background: Numerous studies have shown the beneficial role of fluoride in the primary prevention of dental caries. The aim of the present study was to put into evidence the change in the enamel structure immediately after the application of a fluoride varnish. (2) Methods: A xylitol–fluoride varnish was evaluated. The enamel specimens (<i>n</i> = 10) were analyzed by atomic force microscopy on enamel surface and treatment with fluoride varnish applied. The dimensional topographic analysis was performed by 2D and 3D analysis software. Statistical analysis was performed using SPSS Version 26.00 (IBM, Armonk, NY, USA). A one-sample statistics test was used to identify significant differences (<i>p</i> < 0.05). (3) Results: Surface roughness (Ra) measurements ranged from Ra = 0.039 μm (±0.048), to Ra = 0.049 μm (±0.031), respectively (<i>p</i> < 0.05), with an increase in the surface roughness passing from the intact enamel to the enamel exposed to fluoride varnish. When comparing Ra values of the nonfluorinated enamel and fluorinated enamel, significant differences (<i>p</i> < 0.05) were found, suggesting that the varnish had a protective effect on the enamel surface. (4) Conclusions: Xylitol–fluoride varnish, even in one single short-time application, is effective in reducing the surface roughness of enamel structure exposed to abrasion, thus increasing resistance to dental caries. |
| first_indexed | 2024-03-09T04:39:51Z |
| format | Article |
| id | doaj.art-395aa290614440609c1d285e2f1ecfe7 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T04:39:51Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-395aa290614440609c1d285e2f1ecfe72023-12-03T13:21:43ZengMDPI AGBiomedicines2227-90592022-08-01108190010.3390/biomedicines10081900Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force MicroscopyCatalina Iulia Saveanu0Oana Dragos1Daniela Anistoroaei2Livia Ionela Bobu3Alexandra Ecaterina Saveanu4Adina Armencia5Sorina Mihaela Solomon6Oana Tanculescu7Surgical Department, Faculty of Dental Medicine, University of Medicine and Pharmacy Grigore T. Popa, 700115 Iasi, RomaniaNational Institute of Research-Development for Technical Physics—IFT, 700115 Iasi, RomaniaSurgical Department, Faculty of Dental Medicine, University of Medicine and Pharmacy Grigore T. Popa, 700115 Iasi, RomaniaSurgical Department, Faculty of Dental Medicine, University of Medicine and Pharmacy Grigore T. Popa, 700115 Iasi, RomaniaFaculty of Dental Medicine, University of Medicine and Pharmacy Grigore T. Popa, 700115 Iasi, RomaniaSurgical Department, Faculty of Dental Medicine, University of Medicine and Pharmacy Grigore T. Popa, 700115 Iasi, RomaniaDepartment of Odontology-Periodontology and Fixed Prosthodontics Faculty of Dental Medicine, University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Odontology-Periodontology and Fixed Prosthodontics Faculty of Dental Medicine, University of Medicine and Pharmacy, 700115 Iasi, Romania(1) Background: Numerous studies have shown the beneficial role of fluoride in the primary prevention of dental caries. The aim of the present study was to put into evidence the change in the enamel structure immediately after the application of a fluoride varnish. (2) Methods: A xylitol–fluoride varnish was evaluated. The enamel specimens (<i>n</i> = 10) were analyzed by atomic force microscopy on enamel surface and treatment with fluoride varnish applied. The dimensional topographic analysis was performed by 2D and 3D analysis software. Statistical analysis was performed using SPSS Version 26.00 (IBM, Armonk, NY, USA). A one-sample statistics test was used to identify significant differences (<i>p</i> < 0.05). (3) Results: Surface roughness (Ra) measurements ranged from Ra = 0.039 μm (±0.048), to Ra = 0.049 μm (±0.031), respectively (<i>p</i> < 0.05), with an increase in the surface roughness passing from the intact enamel to the enamel exposed to fluoride varnish. When comparing Ra values of the nonfluorinated enamel and fluorinated enamel, significant differences (<i>p</i> < 0.05) were found, suggesting that the varnish had a protective effect on the enamel surface. (4) Conclusions: Xylitol–fluoride varnish, even in one single short-time application, is effective in reducing the surface roughness of enamel structure exposed to abrasion, thus increasing resistance to dental caries.https://www.mdpi.com/2227-9059/10/8/1900xylitol fluoride varnishatomic force microscopyroughnessenamel |
| spellingShingle | Catalina Iulia Saveanu Oana Dragos Daniela Anistoroaei Livia Ionela Bobu Alexandra Ecaterina Saveanu Adina Armencia Sorina Mihaela Solomon Oana Tanculescu Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy Biomedicines xylitol fluoride varnish atomic force microscopy roughness enamel |
| title | Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy |
| title_full | Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy |
| title_fullStr | Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy |
| title_full_unstemmed | Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy |
| title_short | Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy |
| title_sort | xylitol fluoride varnish in vitro effect analysis on enamel by atomic force microscopy |
| topic | xylitol fluoride varnish atomic force microscopy roughness enamel |
| url | https://www.mdpi.com/2227-9059/10/8/1900 |
| work_keys_str_mv | AT catalinaiuliasaveanu xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT oanadragos xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT danielaanistoroaei xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT liviaionelabobu xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT alexandraecaterinasaveanu xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT adinaarmencia xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT sorinamihaelasolomon xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy AT oanatanculescu xylitolfluoridevarnishinvitroeffectanalysisonenamelbyatomicforcemicroscopy |