| Summary: | Koichi Nishitsuka, Katsuhiro Nishi, Hiroyuki Namba, Yutaka Kaneko, Hidetoshi Yamashita Department of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata, JapanCorrespondence: Koichi NishitsukaDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, JapanTel +81 23-628-5374Fax +81 23-528-5377Email mlc12186@nifty.comPurpose: This study aimed to observe intraoperative changes in macular hole (MH) form using intraoperative optical coherence tomography (iOCT).Methods: A total of 10 eyes from 10 patients with MH who underwent vitrectomy using iOCT from May 2015 to October 2015 at the Yamagata University Hospital were retrospectively evaluated. Accordingly, 25-gauge pars plana vitrectomy using iOCT with internal limiting membrane (ILM) peeling and sulfur hexafluoride gas tamponade was performed on each patient. During surgery, MHs were observed using iOCT over four points, namely, before posterior vitreous detachment (PVD) formation, after PVD formation, after ILM peeling, and after fluid–gas exchange. Thereafter, basal MH diameter and minimum aperture MH diameter were postoperatively analyzed.Results: Before PVD formation, after PVD formation, after ILM peeling, and after fluid–gas exchange, the mean basal MH diameters were 690.7 ± 268.4, 683.3 ± 274.2, 683.7 ± 269.5, and 668.3 ± 261.4 μm, while the mean minimum aperture MH diameters were 278.3 ± 165.2, 283.0 ± 170.2, 257.0 ± 127.8, and 188.0 ± 105.0 μm, respectively. The mean minimum aperture MH diameter decreased significantly after fluid–gas exchange (one-way repeated measures ANOVA, p < 0.05). None of the patients exhibited intraoperative closure of the MHs. However, MH closure was confirmed in all patients after the surgery.Conclusion: None of the patients demonstrated intraoperative MHs closure. Accordingly, the minimum aperture MH diameter was the first change formation to close after fluid–gas exchange.Keywords: macular hole, intraoperative optical coherence tomography, early change
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