Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip

Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip

Bone loss caused by mechanical unloading is a threat to prolonged space flight and human health. Epigenetic modifications play a crucial role in varied biological processes, but the mechanism of histone modification on unloading-induced bone loss has rarely been studied. Here, we discovered for the...

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Bibliographic Details
Main Authors: Lijun Zhang, Liqun Xu, Xiaoyan Zhang, Ke Wang, Yingjun Tan, Gaozhi Li, Yixuan Wang, Tong Xue, Quan Sun, Xinsheng Cao, Ge Zhang, Zebing Hu, Shu Zhang, Fei Shi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
Setdb1
cell proliferation
mechanical unloading
bone loss
Online Access:https://www.mdpi.com/2073-4409/11/16/2580

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