Toxic Wasting Disorders in Sheep
Infectious and parasitic agents have been frequently associated with debilitating and wasting conditions in sheep. The prevalence of these agents has probably undermined the role of toxic causes as contributors to such disorders. In addition, many of these intoxications frequently produce acute clin...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-01-01
|
| Series: | Animals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2615/11/1/229 |
| _version_ | 1797410015669125120 |
|---|---|
| author | Jéssica Molín Fábio S. Mendonça Eileen E. Henderson Akinyi C. Nyaoke Gustavo A. Ramírez Mauricio A. Navarro Francisco A. Uzal Javier Asín |
| author_facet | Jéssica Molín Fábio S. Mendonça Eileen E. Henderson Akinyi C. Nyaoke Gustavo A. Ramírez Mauricio A. Navarro Francisco A. Uzal Javier Asín |
| author_sort | Jéssica Molín |
| collection | DOAJ |
| description | Infectious and parasitic agents have been frequently associated with debilitating and wasting conditions in sheep. The prevalence of these agents has probably undermined the role of toxic causes as contributors to such disorders. In addition, many of these intoxications frequently produce acute clinical disease with specific and characteristic lesions, thus a causal relationship with the toxic substance may be relatively easy to establish. However, persistent exposure to some of these organic or inorganic toxic substances may lead to emaciation, ill-thrift, and poor external aspect. The anti-nutritional factors and alkaloids of several plants, including pyrrolizidine alkaloids, among others, have also been associated with emaciation and/or poor general performance in sheep flocks. In this review, some of these disorders are discussed with an emphasis on clinical signs and lesions, relevant diagnostic aspects, and available therapeutic approaches. In most cases, demonstrating a history of exposure should be one of the most relevant aspects of the diagnostic approach, and removing the animals from the toxic source is the cornerstone of the majority of the treatment strategies. |
| first_indexed | 2024-03-09T04:23:46Z |
| format | Article |
| id | doaj.art-395f825417564e8a8236a42535dd258e |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T04:23:46Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-395f825417564e8a8236a42535dd258e2023-12-03T13:43:05ZengMDPI AGAnimals2076-26152021-01-0111122910.3390/ani11010229Toxic Wasting Disorders in SheepJéssica Molín0Fábio S. Mendonça1Eileen E. Henderson2Akinyi C. Nyaoke3Gustavo A. Ramírez4Mauricio A. Navarro5Francisco A. Uzal6Javier Asín7Animal Science Department, University of Lleida, Lleida 25198, SpainLaboratory of Animal Diagnosis, DMFA/UFRPE, Recife, Pernambuco 52171-900, BrazilCalifornia Animal Health and Food Safety Laboratory (CAHFS), San Bernardino Branch, University of California, Davis, CA 95616, USACalifornia Animal Health and Food Safety Laboratory (CAHFS), San Bernardino Branch, University of California, Davis, CA 95616, USAAnimal Science Department, University of Lleida, Lleida 25198, SpainCalifornia Animal Health and Food Safety Laboratory (CAHFS), San Bernardino Branch, University of California, Davis, CA 95616, USACalifornia Animal Health and Food Safety Laboratory (CAHFS), San Bernardino Branch, University of California, Davis, CA 95616, USACalifornia Animal Health and Food Safety Laboratory (CAHFS), San Bernardino Branch, University of California, Davis, CA 95616, USAInfectious and parasitic agents have been frequently associated with debilitating and wasting conditions in sheep. The prevalence of these agents has probably undermined the role of toxic causes as contributors to such disorders. In addition, many of these intoxications frequently produce acute clinical disease with specific and characteristic lesions, thus a causal relationship with the toxic substance may be relatively easy to establish. However, persistent exposure to some of these organic or inorganic toxic substances may lead to emaciation, ill-thrift, and poor external aspect. The anti-nutritional factors and alkaloids of several plants, including pyrrolizidine alkaloids, among others, have also been associated with emaciation and/or poor general performance in sheep flocks. In this review, some of these disorders are discussed with an emphasis on clinical signs and lesions, relevant diagnostic aspects, and available therapeutic approaches. In most cases, demonstrating a history of exposure should be one of the most relevant aspects of the diagnostic approach, and removing the animals from the toxic source is the cornerstone of the majority of the treatment strategies.https://www.mdpi.com/2076-2615/11/1/229sheepintoxicationspoisonous plantswasting |
| spellingShingle | Jéssica Molín Fábio S. Mendonça Eileen E. Henderson Akinyi C. Nyaoke Gustavo A. Ramírez Mauricio A. Navarro Francisco A. Uzal Javier Asín Toxic Wasting Disorders in Sheep Animals sheep intoxications poisonous plants wasting |
| title | Toxic Wasting Disorders in Sheep |
| title_full | Toxic Wasting Disorders in Sheep |
| title_fullStr | Toxic Wasting Disorders in Sheep |
| title_full_unstemmed | Toxic Wasting Disorders in Sheep |
| title_short | Toxic Wasting Disorders in Sheep |
| title_sort | toxic wasting disorders in sheep |
| topic | sheep intoxications poisonous plants wasting |
| url | https://www.mdpi.com/2076-2615/11/1/229 |
| work_keys_str_mv | AT jessicamolin toxicwastingdisordersinsheep AT fabiosmendonca toxicwastingdisordersinsheep AT eileenehenderson toxicwastingdisordersinsheep AT akinyicnyaoke toxicwastingdisordersinsheep AT gustavoaramirez toxicwastingdisordersinsheep AT mauricioanavarro toxicwastingdisordersinsheep AT franciscoauzal toxicwastingdisordersinsheep AT javierasin toxicwastingdisordersinsheep |