Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health

Moderate wine consumption is often associated with healthy lifestyle habits. The role of wine as a healthy drink is mainly due to its bioactive compounds, which differ according to various viticultural and enological factors. The aim of the present study was to observe the differences in bioactive c...

Full description

Bibliographic Details
Main Authors: Sanja Radeka, Sara Rossi, Ena Bestulić, Irena Budić-Leto, Karin Kovačević Ganić, Ivana Horvat, Igor Lukić, Fumica Orbanić, Teodora Zaninović Jurjević, Štefica Dvornik
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/11/12/1804
_version_ 1797487430211731456
author Sanja Radeka
Sara Rossi
Ena Bestulić
Irena Budić-Leto
Karin Kovačević Ganić
Ivana Horvat
Igor Lukić
Fumica Orbanić
Teodora Zaninović Jurjević
Štefica Dvornik
author_facet Sanja Radeka
Sara Rossi
Ena Bestulić
Irena Budić-Leto
Karin Kovačević Ganić
Ivana Horvat
Igor Lukić
Fumica Orbanić
Teodora Zaninović Jurjević
Štefica Dvornik
author_sort Sanja Radeka
collection DOAJ
description Moderate wine consumption is often associated with healthy lifestyle habits. The role of wine as a healthy drink is mainly due to its bioactive compounds, which differ according to various viticultural and enological factors. The aim of the present study was to observe the differences in bioactive compounds of white and red autochthonous Croatian wines, differing in terms of the grape variety and production technology. Our further aim was to explore the effect of their moderate consumption (200 mL per day) over the course of six weeks on some aspects of health in sixty-six healthy individuals. Participants were divided into eight groups depending on the wines consumed, while one group formed a non-consuming control group. Medical examination and laboratory tests were performed before the start and at the end of the consumption period. Systolic and diastolic blood pressure, total cholesterol, and LDL concentrations decreased. Additionally, an increase in HDL concentrations, and serotonin and dopamine levels, was observed. ALT, ALP, and GGT levels did not significantly increase in consumer groups, although alcohol concentration was relatively high in all the wines. Such results support the beneficial effects of wine-derived bioactive compounds on some health aspects resulting from moderate white and red wine consumption.
first_indexed 2024-03-09T23:48:31Z
format Article
id doaj.art-396583de9fd74dac8b6465efefea094f
institution Directory Open Access Journal
issn 2304-8158
language English
last_indexed 2024-03-09T23:48:31Z
publishDate 2022-06-01
publisher MDPI AG
record_format Article
series Foods
spelling doaj.art-396583de9fd74dac8b6465efefea094f2023-11-23T16:39:20ZengMDPI AGFoods2304-81582022-06-011112180410.3390/foods11121804Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human HealthSanja Radeka0Sara Rossi1Ena Bestulić2Irena Budić-Leto3Karin Kovačević Ganić4Ivana Horvat5Igor Lukić6Fumica Orbanić7Teodora Zaninović Jurjević8Štefica Dvornik9Institute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, CroatiaInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, CroatiaInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, CroatiaInstitute for Adriatic Crops and Karst Reclamation, Put Duilova 11, 21000 Split, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, CroatiaInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, CroatiaInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, CroatiaInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, CroatiaClinical Hospital Centre Rijeka, Krešimirova ul. 42, 51000 Rijeka, CroatiaClinical Hospital Centre Rijeka, Krešimirova ul. 42, 51000 Rijeka, CroatiaModerate wine consumption is often associated with healthy lifestyle habits. The role of wine as a healthy drink is mainly due to its bioactive compounds, which differ according to various viticultural and enological factors. The aim of the present study was to observe the differences in bioactive compounds of white and red autochthonous Croatian wines, differing in terms of the grape variety and production technology. Our further aim was to explore the effect of their moderate consumption (200 mL per day) over the course of six weeks on some aspects of health in sixty-six healthy individuals. Participants were divided into eight groups depending on the wines consumed, while one group formed a non-consuming control group. Medical examination and laboratory tests were performed before the start and at the end of the consumption period. Systolic and diastolic blood pressure, total cholesterol, and LDL concentrations decreased. Additionally, an increase in HDL concentrations, and serotonin and dopamine levels, was observed. ALT, ALP, and GGT levels did not significantly increase in consumer groups, although alcohol concentration was relatively high in all the wines. Such results support the beneficial effects of wine-derived bioactive compounds on some health aspects resulting from moderate white and red wine consumption.https://www.mdpi.com/2304-8158/11/12/1804autochthonous Croatian winesbioactive compoundsmoderate wine consumptionhealth
spellingShingle Sanja Radeka
Sara Rossi
Ena Bestulić
Irena Budić-Leto
Karin Kovačević Ganić
Ivana Horvat
Igor Lukić
Fumica Orbanić
Teodora Zaninović Jurjević
Štefica Dvornik
Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health
Foods
autochthonous Croatian wines
bioactive compounds
moderate wine consumption
health
title Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health
title_full Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health
title_fullStr Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health
title_full_unstemmed Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health
title_short Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health
title_sort bioactive compounds and antioxidant activity of red and white wines produced from autochthonous croatian varieties effect of moderate consumption on human health
topic autochthonous Croatian wines
bioactive compounds
moderate wine consumption
health
url https://www.mdpi.com/2304-8158/11/12/1804
work_keys_str_mv AT sanjaradeka bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT sararossi bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT enabestulic bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT irenabudicleto bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT karinkovacevicganic bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT ivanahorvat bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT igorlukic bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT fumicaorbanic bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT teodorazaninovicjurjevic bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth
AT steficadvornik bioactivecompoundsandantioxidantactivityofredandwhitewinesproducedfromautochthonouscroatianvarietieseffectofmoderateconsumptiononhumanhealth