Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respirator...

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Bibliographic Details
Main Authors: Takuya Adachi, Ja-Mun Chong, Noriko Nakajima, Masahiro Sano, Jun Yamazaki, Ippei Miyamoto, Haruka Nishioka, Hidetaka Akita, Yuko Sato, Michiyo Kataoka, Harutaka Katano, Minoru Tobiume, Tsuyoshi Sekizuka, Kentaro Itokawa, Makoto Kuroda, Tadaki Suzuki
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-09-01
Series:Emerging Infectious Diseases
Subjects:
COVID-19
SARS-CoV-2
cruise
autopsy
diffuse alveolar damage
immunohistochemistry
Online Access:https://wwwnc.cdc.gov/eid/article/26/9/20-1353_article
Description
Summary:An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells.
ISSN:1080-6040
1080-6059

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