Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients
This study was aimed to determine bone formation markers (OST and BALP) and lysyl oxidase in diabetes and non-diabetes Iraqi acromegaly patients in addition to find the relationship among these parameters. The present study conducted 60 acromegalic patients (30 diabetes & 30 non diabetes) a...
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| Format: | Article |
| Language: | English |
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University of Baghdad
2018-05-01
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| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/1864 |
| _version_ | 1818270472758886400 |
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| author | Eiman A. Abass Baydaa Ahmed Abed Sohaib N. Mohsin |
| author_facet | Eiman A. Abass Baydaa Ahmed Abed Sohaib N. Mohsin |
| author_sort | Eiman A. Abass |
| collection | DOAJ |
| description |
This study was aimed to determine bone formation markers (OST and BALP) and lysyl oxidase in diabetes and non-diabetes Iraqi acromegaly patients in addition to find the relationship among these parameters. The present study conducted 60 acromegalic patients (30 diabetes & 30 non diabetes) attending National Diabetes Center / AL-Mustansiriya University/Baghdad, and 30 healthy individuals as a control group aged (35-60) years. All patients were administrated Sandostatin drug, and they were diagnosed by physician in the hospital.FBG, GH, IGF-1, OST, BALP, and LOX were determined in all groups. The results showed a highly significant rise in all parameters (GH, IGF-1, FBG, OST, BALP, and LOX values in serum of all patients when compared with normal individuals. There were a positive highly significant correlations for lysyl oxidase with osteocalcin and a positive significant with BALP in acromegalic patients. We concluded that lysyl oxidase may be a novel biomarkers in endocrine diseases like acromegaly.
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| first_indexed | 2024-12-12T21:10:50Z |
| format | Article |
| id | doaj.art-3967f9635b334f8ab969b4259575377b |
| institution | Directory Open Access Journal |
| issn | 1609-4042 2521-3407 |
| language | English |
| last_indexed | 2024-12-12T21:10:50Z |
| publishDate | 2018-05-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj.art-3967f9635b334f8ab969b4259575377b2022-12-22T00:11:54ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072018-05-0131110.30526/31.1.1864Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic PatientsEiman A. AbassBaydaa Ahmed AbedSohaib N. Mohsin This study was aimed to determine bone formation markers (OST and BALP) and lysyl oxidase in diabetes and non-diabetes Iraqi acromegaly patients in addition to find the relationship among these parameters. The present study conducted 60 acromegalic patients (30 diabetes & 30 non diabetes) attending National Diabetes Center / AL-Mustansiriya University/Baghdad, and 30 healthy individuals as a control group aged (35-60) years. All patients were administrated Sandostatin drug, and they were diagnosed by physician in the hospital.FBG, GH, IGF-1, OST, BALP, and LOX were determined in all groups. The results showed a highly significant rise in all parameters (GH, IGF-1, FBG, OST, BALP, and LOX values in serum of all patients when compared with normal individuals. There were a positive highly significant correlations for lysyl oxidase with osteocalcin and a positive significant with BALP in acromegalic patients. We concluded that lysyl oxidase may be a novel biomarkers in endocrine diseases like acromegaly. https://jih.uobaghdad.edu.iq/index.php/j/article/view/1864Acromegaly, bone formation markers, osteocalcin, BALP, lysyl oxidase. |
| spellingShingle | Eiman A. Abass Baydaa Ahmed Abed Sohaib N. Mohsin Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients Ibn Al-Haitham Journal for Pure and Applied Sciences Acromegaly, bone formation markers, osteocalcin, BALP, lysyl oxidase. |
| title | Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients |
| title_full | Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients |
| title_fullStr | Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients |
| title_full_unstemmed | Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients |
| title_short | Determination of Osteocalcin, Bone Alkaline Phosphatase, and Lysyl Oxidase in Iraqi Acromegalic Patients |
| title_sort | determination of osteocalcin bone alkaline phosphatase and lysyl oxidase in iraqi acromegalic patients |
| topic | Acromegaly, bone formation markers, osteocalcin, BALP, lysyl oxidase. |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/1864 |
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