Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions
We are reporting a simple, efficient and green protocol for the synthesis of chromenes and dihydropyrimidines (products of Knoevenagel and Biginelli reaction, respectively) by the use of silica-supported perchloric acid (HClO4–SiO2) as an effective heterogeneous catalyst. Short reaction times, high...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-07-01
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| Series: | Green Chemistry Letters and Reviews |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/17518253.2018.1510991 |
| _version_ | 1811331205667225600 |
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| author | Leimajam Vartima Chanu Thokchom Prasanta Singh Laishram Ronibala Devi Okram Mukherjee Singh |
| author_facet | Leimajam Vartima Chanu Thokchom Prasanta Singh Laishram Ronibala Devi Okram Mukherjee Singh |
| author_sort | Leimajam Vartima Chanu |
| collection | DOAJ |
| description | We are reporting a simple, efficient and green protocol for the synthesis of chromenes and dihydropyrimidines (products of Knoevenagel and Biginelli reaction, respectively) by the use of silica-supported perchloric acid (HClO4–SiO2) as an effective heterogeneous catalyst. Short reaction times, high product yields, simple procedure and reusability of the catalyst are the superior characteristics of this protocol. |
| first_indexed | 2024-04-13T16:15:31Z |
| format | Article |
| id | doaj.art-396b65ced1294b718450a54f1aec5596 |
| institution | Directory Open Access Journal |
| issn | 1751-8253 1751-7192 |
| language | English |
| last_indexed | 2024-04-13T16:15:31Z |
| publishDate | 2018-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Green Chemistry Letters and Reviews |
| spelling | doaj.art-396b65ced1294b718450a54f1aec55962022-12-22T02:40:04ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922018-07-0111335236010.1080/17518253.2018.15109911510991Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditionsLeimajam Vartima Chanu0Thokchom Prasanta Singh1Laishram Ronibala Devi2Okram Mukherjee Singh3Manipur UniversityManipur UniversityNational Institute of TechnologyManipur UniversityWe are reporting a simple, efficient and green protocol for the synthesis of chromenes and dihydropyrimidines (products of Knoevenagel and Biginelli reaction, respectively) by the use of silica-supported perchloric acid (HClO4–SiO2) as an effective heterogeneous catalyst. Short reaction times, high product yields, simple procedure and reusability of the catalyst are the superior characteristics of this protocol.http://dx.doi.org/10.1080/17518253.2018.1510991Knoevenagel condensationBiginelli reactionchromenesdihydropyrimidinegreen catalyst |
| spellingShingle | Leimajam Vartima Chanu Thokchom Prasanta Singh Laishram Ronibala Devi Okram Mukherjee Singh Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions Green Chemistry Letters and Reviews Knoevenagel condensation Biginelli reaction chromenes dihydropyrimidine green catalyst |
| title | Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions |
| title_full | Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions |
| title_fullStr | Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions |
| title_full_unstemmed | Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions |
| title_short | Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions |
| title_sort | synthesis of bioactive heterocycles using reusable heterogeneous catalyst hclo4 sio2 under solvent free conditions |
| topic | Knoevenagel condensation Biginelli reaction chromenes dihydropyrimidine green catalyst |
| url | http://dx.doi.org/10.1080/17518253.2018.1510991 |
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