Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex
Sustained peripheral somatosensory stimulations, such as high-frequency repetitive somatosensory stimulation (HF-RSS) and vibrated stimulation, are effective in altering the balance between excitation and inhibition in the somatosensory cortex (S1) and motor cortex (M1). A recent study reported that...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2022.962936/full |
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| author | Dat Le Cong Dat Le Cong Dat Le Cong Daisuke Sato Daisuke Sato Koyuki Ikarashi Koyuki Ikarashi Koyuki Ikarashi Koyuki Ikarashi Tomomi Fujimoto Tomomi Fujimoto Genta Ochi Genta Ochi Koya Yamashiro Koya Yamashiro |
| author_facet | Dat Le Cong Dat Le Cong Dat Le Cong Daisuke Sato Daisuke Sato Koyuki Ikarashi Koyuki Ikarashi Koyuki Ikarashi Koyuki Ikarashi Tomomi Fujimoto Tomomi Fujimoto Genta Ochi Genta Ochi Koya Yamashiro Koya Yamashiro |
| author_sort | Dat Le Cong |
| collection | DOAJ |
| description | Sustained peripheral somatosensory stimulations, such as high-frequency repetitive somatosensory stimulation (HF-RSS) and vibrated stimulation, are effective in altering the balance between excitation and inhibition in the somatosensory cortex (S1) and motor cortex (M1). A recent study reported that whole-hand water flow (WF) stimulation induced neural disinhibition in the M1. Based on previous results, we hypothesized that whole-hand WF stimulation would lead to neural disinhibition in the S1 because there is a strong neural connection between M1 and S1 and aimed to examine whether whole-hand WF stimulation would change the neural balance between excitation and inhibition in the S1. Nineteen healthy volunteers were studied by measuring excitation and inhibition in the S1 before and after each of the four 15-min interventions. The excitation and inhibition in the S1 were assessed using somatosensory evoked potentials (SEPs) and paired-pulse inhibition (PPI) induced by single- and paired-pulse stimulations, respectively. The four interventions were as follows: control, whole-hand water immersion, whole-hand WF, and HF-RSS. The results showed no significant changes in SEPs and PPI following any intervention. However, changes in PPI with an interstimulus interval (ISI) of 30 ms were significantly correlated with the baseline value before whole-hand WF. Thus, the present findings indicated that the whole-hand WF stimulation had a greater decreased neural inhibition in participants with higher neural inhibition in the S1 at baseline. Considering previous results on M1, the present results possibly show that S1 has lower plasticity than M1 and that the duration (15 min) of each intervention may not have been enough to alter the balance of excitation and inhibition in the S1. |
| first_indexed | 2024-04-12T11:38:21Z |
| format | Article |
| id | doaj.art-396c4d0c587441369ce595eb94b6b462 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-04-12T11:38:21Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-396c4d0c587441369ce595eb94b6b4622022-12-22T03:34:46ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612022-10-011610.3389/fnhum.2022.962936962936Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortexDat Le Cong0Dat Le Cong1Dat Le Cong2Daisuke Sato3Daisuke Sato4Koyuki Ikarashi5Koyuki Ikarashi6Koyuki Ikarashi7Koyuki Ikarashi8Tomomi Fujimoto9Tomomi Fujimoto10Genta Ochi11Genta Ochi12Koya Yamashiro13Koya Yamashiro14Sports Physiology Laboratory, Department of Health and Sports, Niigata University of Health and Welfare, Niigata, JapanGraduate School of Health and Welfare, Niigata University of Health and Welfare, Niigata, JapanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, JapanSports Physiology Laboratory, Department of Health and Sports, Niigata University of Health and Welfare, Niigata, JapanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, JapanSports Physiology Laboratory, Department of Health and Sports, Niigata University of Health and Welfare, Niigata, JapanGraduate School of Health and Welfare, Niigata University of Health and Welfare, Niigata, JapanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, JapanJapan Society for the Promotion of Science, Tokyo, JapanSports Physiology Laboratory, Department of Health and Sports, Niigata University of Health and Welfare, Niigata, JapanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, JapanSports Physiology Laboratory, Department of Health and Sports, Niigata University of Health and Welfare, Niigata, JapanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, JapanSports Physiology Laboratory, Department of Health and Sports, Niigata University of Health and Welfare, Niigata, JapanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, JapanSustained peripheral somatosensory stimulations, such as high-frequency repetitive somatosensory stimulation (HF-RSS) and vibrated stimulation, are effective in altering the balance between excitation and inhibition in the somatosensory cortex (S1) and motor cortex (M1). A recent study reported that whole-hand water flow (WF) stimulation induced neural disinhibition in the M1. Based on previous results, we hypothesized that whole-hand WF stimulation would lead to neural disinhibition in the S1 because there is a strong neural connection between M1 and S1 and aimed to examine whether whole-hand WF stimulation would change the neural balance between excitation and inhibition in the S1. Nineteen healthy volunteers were studied by measuring excitation and inhibition in the S1 before and after each of the four 15-min interventions. The excitation and inhibition in the S1 were assessed using somatosensory evoked potentials (SEPs) and paired-pulse inhibition (PPI) induced by single- and paired-pulse stimulations, respectively. The four interventions were as follows: control, whole-hand water immersion, whole-hand WF, and HF-RSS. The results showed no significant changes in SEPs and PPI following any intervention. However, changes in PPI with an interstimulus interval (ISI) of 30 ms were significantly correlated with the baseline value before whole-hand WF. Thus, the present findings indicated that the whole-hand WF stimulation had a greater decreased neural inhibition in participants with higher neural inhibition in the S1 at baseline. Considering previous results on M1, the present results possibly show that S1 has lower plasticity than M1 and that the duration (15 min) of each intervention may not have been enough to alter the balance of excitation and inhibition in the S1.https://www.frontiersin.org/articles/10.3389/fnhum.2022.962936/fullwhole-hand water flow stimulationprimary somatosensory cortex (S1)paired-pulse inhibition (PPI)repetitive somatosensory stimulationsomatosensory evoked potentials (SEP) |
| spellingShingle | Dat Le Cong Dat Le Cong Dat Le Cong Daisuke Sato Daisuke Sato Koyuki Ikarashi Koyuki Ikarashi Koyuki Ikarashi Koyuki Ikarashi Tomomi Fujimoto Tomomi Fujimoto Genta Ochi Genta Ochi Koya Yamashiro Koya Yamashiro Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex Frontiers in Human Neuroscience whole-hand water flow stimulation primary somatosensory cortex (S1) paired-pulse inhibition (PPI) repetitive somatosensory stimulation somatosensory evoked potentials (SEP) |
| title | Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex |
| title_full | Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex |
| title_fullStr | Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex |
| title_full_unstemmed | Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex |
| title_short | Effect of whole-hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex |
| title_sort | effect of whole hand water flow stimulation on the neural balance between excitation and inhibition in the primary somatosensory cortex |
| topic | whole-hand water flow stimulation primary somatosensory cortex (S1) paired-pulse inhibition (PPI) repetitive somatosensory stimulation somatosensory evoked potentials (SEP) |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2022.962936/full |
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