Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review

Due to enhanced properties at the nanoscale, nanomaterials (NMs) have been incorporated into foods, food additives, and food packaging materials. Knowledge gaps related to (but not limited to) fate, transport, bioaccumulation, and toxicity of nanomaterials have led to an expedient need to expand res...

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Main Authors: Katrin Loeschner, Monique E. Johnson, Antonio R. Montoro Bustos
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/13/18/2547
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author Katrin Loeschner
Monique E. Johnson
Antonio R. Montoro Bustos
author_facet Katrin Loeschner
Monique E. Johnson
Antonio R. Montoro Bustos
author_sort Katrin Loeschner
collection DOAJ
description Due to enhanced properties at the nanoscale, nanomaterials (NMs) have been incorporated into foods, food additives, and food packaging materials. Knowledge gaps related to (but not limited to) fate, transport, bioaccumulation, and toxicity of nanomaterials have led to an expedient need to expand research efforts in the food research field. While classical techniques can provide information on dilute suspensions, these techniques sample a low throughput of nanoparticles (NPs) in the suspension and are limited in the range of the measurement metrics so orthogonal techniques must be used in tandem to fill in measurement gaps. New and innovative characterization techniques have been developed and optimized for employment in food nano-characterization. Single particle inductively coupled plasma mass spectrometry, a high-throughput nanoparticle characterization technique capable of providing vital measurands of NP-containing samples such as size distribution, number concentration, and NP evolution has been employed as a characterization technique in food research since its inception. Here, we offer a short, critical review highlighting existing studies that employ spICP-MS in food research with a particular focus on method validation and trends in sample preparation and spICP-MS methodology. Importantly, we identify and address areas in research as well as offer insights into yet to be addressed knowledge gaps in methodology.
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spelling doaj.art-396f2d62ba3b4647a9c365e5b41d65b12023-11-19T12:14:31ZengMDPI AGNanomaterials2079-49912023-09-011318254710.3390/nano13182547Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short ReviewKatrin Loeschner0Monique E. Johnson1Antonio R. Montoro Bustos2Research Group for Analytical Food Chemistry, National Food Institute, Technical University of Denmark, 2800 Kgs. Lyngby, DenmarkMaterial Measurement Laboratory, Chemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD 20899, USAMaterial Measurement Laboratory, Chemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD 20899, USADue to enhanced properties at the nanoscale, nanomaterials (NMs) have been incorporated into foods, food additives, and food packaging materials. Knowledge gaps related to (but not limited to) fate, transport, bioaccumulation, and toxicity of nanomaterials have led to an expedient need to expand research efforts in the food research field. While classical techniques can provide information on dilute suspensions, these techniques sample a low throughput of nanoparticles (NPs) in the suspension and are limited in the range of the measurement metrics so orthogonal techniques must be used in tandem to fill in measurement gaps. New and innovative characterization techniques have been developed and optimized for employment in food nano-characterization. Single particle inductively coupled plasma mass spectrometry, a high-throughput nanoparticle characterization technique capable of providing vital measurands of NP-containing samples such as size distribution, number concentration, and NP evolution has been employed as a characterization technique in food research since its inception. Here, we offer a short, critical review highlighting existing studies that employ spICP-MS in food research with a particular focus on method validation and trends in sample preparation and spICP-MS methodology. Importantly, we identify and address areas in research as well as offer insights into yet to be addressed knowledge gaps in methodology.https://www.mdpi.com/2079-4991/13/18/2547inorganic nanoparticlessingle particle ICP-MSfoodfood additivessample collectionsample preparation
spellingShingle Katrin Loeschner
Monique E. Johnson
Antonio R. Montoro Bustos
Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review
Nanomaterials
inorganic nanoparticles
single particle ICP-MS
food
food additives
sample collection
sample preparation
title Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review
title_full Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review
title_fullStr Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review
title_full_unstemmed Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review
title_short Application of Single Particle ICP-MS for the Determination of Inorganic Nanoparticles in Food Additives and Food: A Short Review
title_sort application of single particle icp ms for the determination of inorganic nanoparticles in food additives and food a short review
topic inorganic nanoparticles
single particle ICP-MS
food
food additives
sample collection
sample preparation
url https://www.mdpi.com/2079-4991/13/18/2547
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AT moniqueejohnson applicationofsingleparticleicpmsforthedeterminationofinorganicnanoparticlesinfoodadditivesandfoodashortreview
AT antoniormontorobustos applicationofsingleparticleicpmsforthedeterminationofinorganicnanoparticlesinfoodadditivesandfoodashortreview