Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis.
Significance of processes of freelipid peroxidation, local immunological disorders and features of biocenosis of periodontal tissues and their role in the occurrence of purulent process in the periodontium in 64 patients with chronic generalized periodontitis of I-II severity degree is proved. By to...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2016-12-01
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| Series: | Medičnì Perspektivi |
| Subjects: | |
| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/91472 |
| _version_ | 1826909096760049664 |
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| author | А. А. Gudaryan N. B. Kuznyak I. I. Dronik |
| author_facet | А. А. Gudaryan N. B. Kuznyak I. I. Dronik |
| author_sort | А. А. Gudaryan |
| collection | DOAJ |
| description | Significance of processes of freelipid peroxidation, local immunological disorders and features of biocenosis of periodontal tissues and their role in the occurrence of purulent process in the periodontium in 64 patients with chronic generalized periodontitis of I-II severity degree is proved. By total of results of clinical, microbiological and metabolic studies in patients it was showed, that formation of purulent process in periodontal tissues is due to the dominance in the gingival econiche of staphylococus, fuzospiliar infection, deficiency of secretory immunity of the oral mucosa, intensity of lipid peroxidation and inhibition of antioxidant protection. It was found that the normalization of the levels of immunoglobulins, especially of sIgA, cytokines (IL-1β, TNF-α), the operation of POL and AOP are the main markers of improved clinical picture of the disease. |
| first_indexed | 2024-12-22T06:01:11Z |
| format | Article |
| id | doaj.art-3970a1e8f5fe41db875ded3a076a466d |
| institution | Directory Open Access Journal |
| issn | 2307-0404 |
| language | English |
| last_indexed | 2025-02-17T09:34:54Z |
| publishDate | 2016-12-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj.art-3970a1e8f5fe41db875ded3a076a466d2025-01-02T09:42:50ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042016-12-012149810510.26641/2307-0404.2016.4.9147291472Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis.А. А. GudaryanN. B. KuznyakI. I. DronikSignificance of processes of freelipid peroxidation, local immunological disorders and features of biocenosis of periodontal tissues and their role in the occurrence of purulent process in the periodontium in 64 patients with chronic generalized periodontitis of I-II severity degree is proved. By total of results of clinical, microbiological and metabolic studies in patients it was showed, that formation of purulent process in periodontal tissues is due to the dominance in the gingival econiche of staphylococus, fuzospiliar infection, deficiency of secretory immunity of the oral mucosa, intensity of lipid peroxidation and inhibition of antioxidant protection. It was found that the normalization of the levels of immunoglobulins, especially of sIgA, cytokines (IL-1β, TNF-α), the operation of POL and AOP are the main markers of improved clinical picture of the disease.http://journals.uran.ua/index.php/2307-0404/article/view/91472generalized periodontitislipid peroxidationimmunodeficiencybiocenosis |
| spellingShingle | А. А. Gudaryan N. B. Kuznyak I. I. Dronik Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. Medičnì Perspektivi generalized periodontitis lipid peroxidation immunodeficiency biocenosis |
| title | Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. |
| title_full | Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. |
| title_fullStr | Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. |
| title_full_unstemmed | Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. |
| title_short | Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. |
| title_sort | clinical microbiological immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis |
| topic | generalized periodontitis lipid peroxidation immunodeficiency biocenosis |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/91472 |
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