Synaptic and circuit development of the primary sensory cortex
Brain development: critical periods in infancy Insights into how the brain responds to environmental stimuli during early infancy may inform brain disorder therapies. The brains of vertebrates, including humans, go through a distinctive ‘critical period’ after birth, when the nervous system optimize...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2018-04-01
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| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-018-0029-x |
| _version_ | 1818608733806133248 |
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| author | Se-Young Choi |
| author_facet | Se-Young Choi |
| author_sort | Se-Young Choi |
| collection | DOAJ |
| description | Brain development: critical periods in infancy Insights into how the brain responds to environmental stimuli during early infancy may inform brain disorder therapies. The brains of vertebrates, including humans, go through a distinctive ‘critical period’ after birth, when the nervous system optimizes neural circuits according to sensory experiences. This phase, if disrupted, may impact on healthy development. Se-Young Choi at Seoul National University School of Dentistry, South Korea reviewed current understanding of the mechanisms involved in this critical period, particularly in the primary sensory cortex. Certain neurons and genes are known to play key roles, and it is possible that manipulating sensory inputs at specific times could achieve specific developmental results. Novel technologies will reveal how the body regulates neural circuits and could one day enable scientists to restore normal functioning in patients with brain disorders such as autism. |
| first_indexed | 2024-12-16T14:47:21Z |
| format | Article |
| id | doaj.art-3971462eed1b405ba2acfb83b878cb43 |
| institution | Directory Open Access Journal |
| issn | 2092-6413 |
| language | English |
| last_indexed | 2024-12-16T14:47:21Z |
| publishDate | 2018-04-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Experimental and Molecular Medicine |
| spelling | doaj.art-3971462eed1b405ba2acfb83b878cb432022-12-21T22:27:44ZengNature Publishing GroupExperimental and Molecular Medicine2092-64132018-04-015041910.1038/s12276-018-0029-xSynaptic and circuit development of the primary sensory cortexSe-Young Choi0Department of Physiology and Dental Research Institute, Seoul National University School of DentistryBrain development: critical periods in infancy Insights into how the brain responds to environmental stimuli during early infancy may inform brain disorder therapies. The brains of vertebrates, including humans, go through a distinctive ‘critical period’ after birth, when the nervous system optimizes neural circuits according to sensory experiences. This phase, if disrupted, may impact on healthy development. Se-Young Choi at Seoul National University School of Dentistry, South Korea reviewed current understanding of the mechanisms involved in this critical period, particularly in the primary sensory cortex. Certain neurons and genes are known to play key roles, and it is possible that manipulating sensory inputs at specific times could achieve specific developmental results. Novel technologies will reveal how the body regulates neural circuits and could one day enable scientists to restore normal functioning in patients with brain disorders such as autism.https://doi.org/10.1038/s12276-018-0029-x |
| spellingShingle | Se-Young Choi Synaptic and circuit development of the primary sensory cortex Experimental and Molecular Medicine |
| title | Synaptic and circuit development of the primary sensory cortex |
| title_full | Synaptic and circuit development of the primary sensory cortex |
| title_fullStr | Synaptic and circuit development of the primary sensory cortex |
| title_full_unstemmed | Synaptic and circuit development of the primary sensory cortex |
| title_short | Synaptic and circuit development of the primary sensory cortex |
| title_sort | synaptic and circuit development of the primary sensory cortex |
| url | https://doi.org/10.1038/s12276-018-0029-x |
| work_keys_str_mv | AT seyoungchoi synapticandcircuitdevelopmentoftheprimarysensorycortex |