Overexpression Cathepsin D Contributes to Perineural Invasion of Salivary Adenoid Cystic Carcinoma

Overexpression Cathepsin D Contributes to Perineural Invasion of Salivary Adenoid Cystic Carcinoma

Objective: Cathepsin D (CTSD) is a pivotal orchestrator in the occurrence and development of tumors. Recently, CTSD was detected in salivary adenoid cystic carcinoma (SACC). However, its functional role in perineural invasion (PNI) of SACC remained elusive. We conducted the present study to detect t...

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Bibliographic Details
Main Authors: Mei Zhang, Jia-shun Wu, Xiao Yang, Xin Pang, Li Li, Sha-sha Wang, Jing-biao Wu, Ya-jie Tang, Xin-hua Liang, Min Zheng, Ya-ling Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
cathepsin D (CTSD)
salivary adenoid cystic carcinoma (SACC)
perineural invasion (PNI)
invasion frontier
cytoskeletal organization
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00492/full

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