bZIPs and WRKYs: two large transcription factor families executing two different functional strategies
bZIPs and WRKYs are two important plant transcription factor families regulating diverse developmental and stress-related processes. Since a partial overlap in these biological processes is obvious, it can be speculated that they fulfill non-redundant functions in a complex regulatory network. Here...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-04-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00169/full |
| _version_ | 1818511305973170176 |
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| author | Carles eMarco Llorca Maren ePotschin Ulrike eZentgraf |
| author_facet | Carles eMarco Llorca Maren ePotschin Ulrike eZentgraf |
| author_sort | Carles eMarco Llorca |
| collection | DOAJ |
| description | bZIPs and WRKYs are two important plant transcription factor families regulating diverse developmental and stress-related processes. Since a partial overlap in these biological processes is obvious, it can be speculated that they fulfill non-redundant functions in a complex regulatory network. Here, we focus on the regulatory mechanisms that are so far described for bZIPs and WRKYs. bZIP factors need to heterodimerize for DNA-binding and regulation of transcription, and based on a bioinformatics approach, bZIPs can build up more than the double of protein interactions than WRKYs. In contrast, an enrichment of the WRKY DNA-binding motifs can be found in WRKY promoters, a phenomenon which is not observed for the bZIP family. Thus, the two transcription factor families follow two different functional strategies in which WRKYs regulate each other’s transcription in a transcriptional network whereas bZIP action relies on intensive heterodimerization. |
| first_indexed | 2024-12-10T23:31:32Z |
| format | Article |
| id | doaj.art-39736652b36649c6ba9d92b0e979757f |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-10T23:31:32Z |
| publishDate | 2014-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-39736652b36649c6ba9d92b0e979757f2022-12-22T01:29:20ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2014-04-01510.3389/fpls.2014.0016979057bZIPs and WRKYs: two large transcription factor families executing two different functional strategiesCarles eMarco Llorca0Maren ePotschin1Ulrike eZentgraf2University of Tuebingen, GermanyUniversity of Tuebingen, GermanyUniversity of Tuebingen, GermanybZIPs and WRKYs are two important plant transcription factor families regulating diverse developmental and stress-related processes. Since a partial overlap in these biological processes is obvious, it can be speculated that they fulfill non-redundant functions in a complex regulatory network. Here, we focus on the regulatory mechanisms that are so far described for bZIPs and WRKYs. bZIP factors need to heterodimerize for DNA-binding and regulation of transcription, and based on a bioinformatics approach, bZIPs can build up more than the double of protein interactions than WRKYs. In contrast, an enrichment of the WRKY DNA-binding motifs can be found in WRKY promoters, a phenomenon which is not observed for the bZIP family. Thus, the two transcription factor families follow two different functional strategies in which WRKYs regulate each other’s transcription in a transcriptional network whereas bZIP action relies on intensive heterodimerization.http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00169/fullbZIPsWRKYsDNA-bindingheterodimerizationregulatory mechanismsG/C box accumulation |
| spellingShingle | Carles eMarco Llorca Maren ePotschin Ulrike eZentgraf bZIPs and WRKYs: two large transcription factor families executing two different functional strategies Frontiers in Plant Science bZIPs WRKYs DNA-binding heterodimerization regulatory mechanisms G/C box accumulation |
| title | bZIPs and WRKYs: two large transcription factor families executing two different functional strategies |
| title_full | bZIPs and WRKYs: two large transcription factor families executing two different functional strategies |
| title_fullStr | bZIPs and WRKYs: two large transcription factor families executing two different functional strategies |
| title_full_unstemmed | bZIPs and WRKYs: two large transcription factor families executing two different functional strategies |
| title_short | bZIPs and WRKYs: two large transcription factor families executing two different functional strategies |
| title_sort | bzips and wrkys two large transcription factor families executing two different functional strategies |
| topic | bZIPs WRKYs DNA-binding heterodimerization regulatory mechanisms G/C box accumulation |
| url | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00169/full |
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