Pulmonary delivery of influenza vaccine formulations in cotton rats: site of deposition plays a minor role in the protective efficacy against clinical isolate of H1N1pdm virus

Pulmonary delivery of influenza vaccine formulations in cotton rats: site of deposition plays a minor role in the protective efficacy against clinical isolate of H1N1pdm virus

Administration of influenza vaccines to the lungs could be an attractive alternative to conventional parenteral administration. In this study, we investigated the deposition site of pulmonary delivered liquid and powder influenza vaccine formulations and its relation to their immunogenicity and prot...

Full description

Bibliographic Details
Main Authors: Yoshita Bhide, Jasmine Tomar, Wei Dong, Jacqueline de Vries-Idema, Henderik W. Frijlink, Anke Huckriede, Wouter L. J. Hinrichs
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
whole inactivated influenza virus vaccine
inhalation
deposition
immunogenicity
protection
Online Access:http://dx.doi.org/10.1080/10717544.2018.1435748

Similar Items

Similar Items