Blood Flow Modeling in Coronary Arteries: A Review
Atherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substance...
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MDPI AG
2021-01-01
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Series: | Fluids |
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Online Access: | https://www.mdpi.com/2311-5521/6/2/53 |
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author | Violeta Carvalho Diana Pinho Rui A. Lima José Carlos Teixeira Senhorinha Teixeira |
author_facet | Violeta Carvalho Diana Pinho Rui A. Lima José Carlos Teixeira Senhorinha Teixeira |
author_sort | Violeta Carvalho |
collection | DOAJ |
description | Atherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substances on the arterial wall, narrowing its lumen. To date, many hemodynamic studies have been conducted experimentally and/or numerically; however, this disease is not yet fully understood. For this reason, the research of this pathology is still ongoing, mainly, resorting to computational methods. These have been increasingly used in biomedical research of atherosclerosis because of their high-performance hardware and software. Taking into account the attempts that have been made in computational techniques to simulate realistic conditions of blood flow in both diseased and healthy arteries, the present review aims to give an overview of the most recent numerical studies focused on coronary arteries, by addressing the blood viscosity models, and applied physiological flow conditions. In general, regardless of the boundary conditions, numerical studies have been contributed to a better understanding of the development of this disease, its diagnosis, and its treatment. |
first_indexed | 2024-03-09T03:52:19Z |
format | Article |
id | doaj.art-39781989a11142e4b937c7d65498808a |
institution | Directory Open Access Journal |
issn | 2311-5521 |
language | English |
last_indexed | 2024-03-09T03:52:19Z |
publishDate | 2021-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Fluids |
spelling | doaj.art-39781989a11142e4b937c7d65498808a2023-12-03T14:25:00ZengMDPI AGFluids2311-55212021-01-01625310.3390/fluids6020053Blood Flow Modeling in Coronary Arteries: A ReviewVioleta Carvalho0Diana Pinho1Rui A. Lima2José Carlos Teixeira3Senhorinha Teixeira4MEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalMEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalMEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalMEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalALGORITMI Centre (CAlg), University of Minho, 4800-058 Guimarães, PortugalAtherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substances on the arterial wall, narrowing its lumen. To date, many hemodynamic studies have been conducted experimentally and/or numerically; however, this disease is not yet fully understood. For this reason, the research of this pathology is still ongoing, mainly, resorting to computational methods. These have been increasingly used in biomedical research of atherosclerosis because of their high-performance hardware and software. Taking into account the attempts that have been made in computational techniques to simulate realistic conditions of blood flow in both diseased and healthy arteries, the present review aims to give an overview of the most recent numerical studies focused on coronary arteries, by addressing the blood viscosity models, and applied physiological flow conditions. In general, regardless of the boundary conditions, numerical studies have been contributed to a better understanding of the development of this disease, its diagnosis, and its treatment.https://www.mdpi.com/2311-5521/6/2/53atherosclerosiscoronary arterieshemodynamicsnumerical methods |
spellingShingle | Violeta Carvalho Diana Pinho Rui A. Lima José Carlos Teixeira Senhorinha Teixeira Blood Flow Modeling in Coronary Arteries: A Review Fluids atherosclerosis coronary arteries hemodynamics numerical methods |
title | Blood Flow Modeling in Coronary Arteries: A Review |
title_full | Blood Flow Modeling in Coronary Arteries: A Review |
title_fullStr | Blood Flow Modeling in Coronary Arteries: A Review |
title_full_unstemmed | Blood Flow Modeling in Coronary Arteries: A Review |
title_short | Blood Flow Modeling in Coronary Arteries: A Review |
title_sort | blood flow modeling in coronary arteries a review |
topic | atherosclerosis coronary arteries hemodynamics numerical methods |
url | https://www.mdpi.com/2311-5521/6/2/53 |
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