Blood Flow Modeling in Coronary Arteries: A Review

Atherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substance...

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Main Authors: Violeta Carvalho, Diana Pinho, Rui A. Lima, José Carlos Teixeira, Senhorinha Teixeira
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Fluids
Subjects:
Online Access:https://www.mdpi.com/2311-5521/6/2/53
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author Violeta Carvalho
Diana Pinho
Rui A. Lima
José Carlos Teixeira
Senhorinha Teixeira
author_facet Violeta Carvalho
Diana Pinho
Rui A. Lima
José Carlos Teixeira
Senhorinha Teixeira
author_sort Violeta Carvalho
collection DOAJ
description Atherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substances on the arterial wall, narrowing its lumen. To date, many hemodynamic studies have been conducted experimentally and/or numerically; however, this disease is not yet fully understood. For this reason, the research of this pathology is still ongoing, mainly, resorting to computational methods. These have been increasingly used in biomedical research of atherosclerosis because of their high-performance hardware and software. Taking into account the attempts that have been made in computational techniques to simulate realistic conditions of blood flow in both diseased and healthy arteries, the present review aims to give an overview of the most recent numerical studies focused on coronary arteries, by addressing the blood viscosity models, and applied physiological flow conditions. In general, regardless of the boundary conditions, numerical studies have been contributed to a better understanding of the development of this disease, its diagnosis, and its treatment.
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spelling doaj.art-39781989a11142e4b937c7d65498808a2023-12-03T14:25:00ZengMDPI AGFluids2311-55212021-01-01625310.3390/fluids6020053Blood Flow Modeling in Coronary Arteries: A ReviewVioleta Carvalho0Diana Pinho1Rui A. Lima2José Carlos Teixeira3Senhorinha Teixeira4MEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalMEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalMEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalMEtRICs Research Center, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, PortugalALGORITMI Centre (CAlg), University of Minho, 4800-058 Guimarães, PortugalAtherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substances on the arterial wall, narrowing its lumen. To date, many hemodynamic studies have been conducted experimentally and/or numerically; however, this disease is not yet fully understood. For this reason, the research of this pathology is still ongoing, mainly, resorting to computational methods. These have been increasingly used in biomedical research of atherosclerosis because of their high-performance hardware and software. Taking into account the attempts that have been made in computational techniques to simulate realistic conditions of blood flow in both diseased and healthy arteries, the present review aims to give an overview of the most recent numerical studies focused on coronary arteries, by addressing the blood viscosity models, and applied physiological flow conditions. In general, regardless of the boundary conditions, numerical studies have been contributed to a better understanding of the development of this disease, its diagnosis, and its treatment.https://www.mdpi.com/2311-5521/6/2/53atherosclerosiscoronary arterieshemodynamicsnumerical methods
spellingShingle Violeta Carvalho
Diana Pinho
Rui A. Lima
José Carlos Teixeira
Senhorinha Teixeira
Blood Flow Modeling in Coronary Arteries: A Review
Fluids
atherosclerosis
coronary arteries
hemodynamics
numerical methods
title Blood Flow Modeling in Coronary Arteries: A Review
title_full Blood Flow Modeling in Coronary Arteries: A Review
title_fullStr Blood Flow Modeling in Coronary Arteries: A Review
title_full_unstemmed Blood Flow Modeling in Coronary Arteries: A Review
title_short Blood Flow Modeling in Coronary Arteries: A Review
title_sort blood flow modeling in coronary arteries a review
topic atherosclerosis
coronary arteries
hemodynamics
numerical methods
url https://www.mdpi.com/2311-5521/6/2/53
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