Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study
The association between oral frailty (OFr) and body action has been investigated, but its association with systemic function remains unclear. Therefore, this cross-sectional study examined the association between OFr with decreased bone mineral density (BMD) and renal function in residents of Shika...
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MDPI AG
2023-01-01
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| author | Shingo Nakai Fumihiko Suzuki Shigefumi Okamoto Sakae Miyagi Hiromasa Tsujiguchi Akinori Hara Thao Thi Thu Nguyen Yukari Shimizu Koichiro Hayashi Keita Suzuki Tomoko Kasahara Masaharu Nakamura Chie Takazawa Takayuki Kannon Atsushi Tajima Hirohito Tsuboi Noriyoshi Ogino Tadashi Konoshita Toshinari Takamura Hiroyuki Nakamura |
| author_facet | Shingo Nakai Fumihiko Suzuki Shigefumi Okamoto Sakae Miyagi Hiromasa Tsujiguchi Akinori Hara Thao Thi Thu Nguyen Yukari Shimizu Koichiro Hayashi Keita Suzuki Tomoko Kasahara Masaharu Nakamura Chie Takazawa Takayuki Kannon Atsushi Tajima Hirohito Tsuboi Noriyoshi Ogino Tadashi Konoshita Toshinari Takamura Hiroyuki Nakamura |
| author_sort | Shingo Nakai |
| collection | DOAJ |
| description | The association between oral frailty (OFr) and body action has been investigated, but its association with systemic function remains unclear. Therefore, this cross-sectional study examined the association between OFr with decreased bone mineral density (BMD) and renal function in residents of Shika town, Ishikawa Prefecture, Japan aged ≥40 years. This study included 400 inhabitants. The OFr total score was assessed using three oral domains in the Kihon Checklist (a self-reported comprehensive health checklist), the number of teeth, and brushing frequency per day. Measurements were the estimated glomerular filtration rate (eGFR) and the osteo-sono assessment index (OSI). Using a two-way analysis of covariance (<i>p</i> = 0.002), significantly lower OSI was indicated in the eGFR < 60 and OFr group than in the eGFR of < 60 and non-OFr group after adjusting for age, body mass index, and drinking and smoking status as confounding factors. Multiple logistic regression analysis confirmed this relationship (<i>p</i> = 0.006). Therefore, lower BMD seems to be associated with lower renal function only when accompanied by OFr. Further longitudinal studies are needed to confirm these results. |
| first_indexed | 2024-03-11T09:43:38Z |
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| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-11T09:43:38Z |
| publishDate | 2023-01-01 |
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| series | Healthcare |
| spelling | doaj.art-397a2f00810b4e25a7175652d43482992023-11-16T16:43:33ZengMDPI AGHealthcare2227-90322023-01-0111331410.3390/healthcare11030314Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika StudyShingo Nakai0Fumihiko Suzuki1Shigefumi Okamoto2Sakae Miyagi3Hiromasa Tsujiguchi4Akinori Hara5Thao Thi Thu Nguyen6Yukari Shimizu7Koichiro Hayashi8Keita Suzuki9Tomoko Kasahara10Masaharu Nakamura11Chie Takazawa12Takayuki Kannon13Atsushi Tajima14Hirohito Tsuboi15Noriyoshi Ogino16Tadashi Konoshita17Toshinari Takamura18Hiroyuki Nakamura19Department of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanAdvanced Health Care Science Research Unit, Innovative Integrated Bio-Research Core, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-0942, JapanInnovative Clinical Research Center, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8641, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanFaculty of Public Health, Haiphong University of Medicine and Pharmacy, Ngo Quyen, Hai Phong 180000, VietnamFaculty of Health Sciences, Department of Nursing, Komatsu University, 14-1 Mukaimotorimachi, Komatsu 923-0961, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanAdvanced Preventive Medical Sciences Research Center, Kanazawa University, 1-13 Takaramachi, Kanazawa 920-8640, JapanAdvanced Preventive Medical Sciences Research Center, Kanazawa University, 1-13 Takaramachi, Kanazawa 920-8640, JapanGraduate School of Human Nursing, The University of Shiga Prefecture, 2500 Hassaka-cho, Hikone 522-8533, JapanDepartment of Environmental Medicine, Faculty of Medicine, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, JapanThird Department of Internal Medicine, University of Fukui Faculty of Medical Sciences, 23-3 Matsuoka Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, JapanDepartment of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa 920-8640, JapanDepartment of Hygiene and Public Health, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, JapanThe association between oral frailty (OFr) and body action has been investigated, but its association with systemic function remains unclear. Therefore, this cross-sectional study examined the association between OFr with decreased bone mineral density (BMD) and renal function in residents of Shika town, Ishikawa Prefecture, Japan aged ≥40 years. This study included 400 inhabitants. The OFr total score was assessed using three oral domains in the Kihon Checklist (a self-reported comprehensive health checklist), the number of teeth, and brushing frequency per day. Measurements were the estimated glomerular filtration rate (eGFR) and the osteo-sono assessment index (OSI). Using a two-way analysis of covariance (<i>p</i> = 0.002), significantly lower OSI was indicated in the eGFR < 60 and OFr group than in the eGFR of < 60 and non-OFr group after adjusting for age, body mass index, and drinking and smoking status as confounding factors. Multiple logistic regression analysis confirmed this relationship (<i>p</i> = 0.006). Therefore, lower BMD seems to be associated with lower renal function only when accompanied by OFr. Further longitudinal studies are needed to confirm these results.https://www.mdpi.com/2227-9032/11/3/314estimated glomerular filtration ratelogistic modelsoral frailtyosteo-sono assessment index |
| spellingShingle | Shingo Nakai Fumihiko Suzuki Shigefumi Okamoto Sakae Miyagi Hiromasa Tsujiguchi Akinori Hara Thao Thi Thu Nguyen Yukari Shimizu Koichiro Hayashi Keita Suzuki Tomoko Kasahara Masaharu Nakamura Chie Takazawa Takayuki Kannon Atsushi Tajima Hirohito Tsuboi Noriyoshi Ogino Tadashi Konoshita Toshinari Takamura Hiroyuki Nakamura Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study Healthcare estimated glomerular filtration rate logistic models oral frailty osteo-sono assessment index |
| title | Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study |
| title_full | Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study |
| title_fullStr | Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study |
| title_full_unstemmed | Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study |
| title_short | Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study |
| title_sort | association between bone mineral density and oral frailty on renal function findings from the shika study |
| topic | estimated glomerular filtration rate logistic models oral frailty osteo-sono assessment index |
| url | https://www.mdpi.com/2227-9032/11/3/314 |
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