Constituents of stable commensal microbiota imply diverse colonic epithelial cell reactivity in patients with ulcerative colitis

Constituents of stable commensal microbiota imply diverse colonic epithelial cell reactivity in patients with ulcerative colitis

Abstract Background Despite extensive research on microbiome alterations in ulcerative colitis (UC), the role of the constituent stable microbiota remains unclear. Results This study, employing 16S rRNA-gene sequencing, uncovers a persistent microbial imbalance in both active and quiescent UC patien...

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Main Authors: Ruta Inciuraite, Rolandas Gedgaudas, Rokas Lukosevicius, Deimante Tilinde, Rima Ramonaite, Alexander Link, Neringa Kasetiene, Mindaugas Malakauskas, Gediminas Kiudelis, Laimas Virginijus Jonaitis, Juozas Kupcinskas, Simonas Juzenas, Jurgita Skieceviciene
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Gut Pathogens
Subjects:
Ulcerative colitis
Gut microbiota
Escherichia coli
Phocaeicola vulgatus
Colonic epithelial organoids
Colonic epithelial barrier
Online Access:https://doi.org/10.1186/s13099-024-00612-0

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