Mexiletine Reverses Oxaliplatin-Induced Neuropathic Pain in Rats

Mexiletine Reverses Oxaliplatin-Induced Neuropathic Pain in Rats

Oxaliplatin is a platinum-based chemotherapy drug characterized by the development of acute and chronic peripheral neuropathies. Mexiletine, an orally available Na+-channel blocker, has widely been used in patients with chronic painful diabetic neuropathy. In the present study, we examined the effec...

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Bibliographic Details
Main Authors:	Nobuaki Egashira, Shingo Hirakawa, Takehiro Kawashiri, Takahisa Yano, Hiroaki Ikesue, Ryozo Oishi
Format:	Article
Language:	English
Published:	Elsevier 2010-01-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861319309855

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