Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21
Down syndrome (DS, trisomy 21), is the most common viable chromosomal disorder, with an incidence of 1 in 800 live births. Its phenotypic characteristics include intellectual impairment and several other developmental abnormalities, for the majority of which the pathogenetic mechanisms remain unknow...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-12-01
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| Series: | Genomics Data |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213596014000646 |
| _version_ | 1817987536088203264 |
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| author | Youssef Hibaoui Iwona Grad Audrey Letourneau Federico A. Santoni Stylianos E. Antonarakis Anis Feki |
| author_facet | Youssef Hibaoui Iwona Grad Audrey Letourneau Federico A. Santoni Stylianos E. Antonarakis Anis Feki |
| author_sort | Youssef Hibaoui |
| collection | DOAJ |
| description | Down syndrome (DS, trisomy 21), is the most common viable chromosomal disorder, with an incidence of 1 in 800 live births. Its phenotypic characteristics include intellectual impairment and several other developmental abnormalities, for the majority of which the pathogenetic mechanisms remain unknown. In this “Data in Brief” paper, we sum up the whole genome analysis by mRNA sequencing of normal and DS induced pluripotent stem cells that was recently published by Hibaoui et al. in EMBO molecular medicine. |
| first_indexed | 2024-04-14T00:23:35Z |
| format | Article |
| id | doaj.art-398912301e064da2b8608ff1217dd4d9 |
| institution | Directory Open Access Journal |
| issn | 2213-5960 |
| language | English |
| last_indexed | 2024-04-14T00:23:35Z |
| publishDate | 2014-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Genomics Data |
| spelling | doaj.art-398912301e064da2b8608ff1217dd4d92022-12-22T02:22:52ZengElsevierGenomics Data2213-59602014-12-012C22622910.1016/j.gdata.2014.07.006Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21Youssef Hibaoui0Iwona Grad1Audrey Letourneau2Federico A. Santoni3Stylianos E. Antonarakis4Anis Feki5Stem Cell Research Laboratory, Department of Obstetrics and Gynecology, Geneva University Hospitals, 30 bd de la Cluse, CH-1211 Geneva, SwitzerlandStem Cell Research Laboratory, Department of Obstetrics and Gynecology, Geneva University Hospitals, 30 bd de la Cluse, CH-1211 Geneva, SwitzerlandDepartment of Genetic Medicine and Development, University of Geneva Medical School and Geneva University Hospitals, 1 rue Michel-Servet, CH-1211 Geneva, SwitzerlandDepartment of Genetic Medicine and Development, University of Geneva Medical School and Geneva University Hospitals, 1 rue Michel-Servet, CH-1211 Geneva, SwitzerlandDepartment of Genetic Medicine and Development, University of Geneva Medical School and Geneva University Hospitals, 1 rue Michel-Servet, CH-1211 Geneva, SwitzerlandStem Cell Research Laboratory, Department of Obstetrics and Gynecology, Geneva University Hospitals, 30 bd de la Cluse, CH-1211 Geneva, SwitzerlandDown syndrome (DS, trisomy 21), is the most common viable chromosomal disorder, with an incidence of 1 in 800 live births. Its phenotypic characteristics include intellectual impairment and several other developmental abnormalities, for the majority of which the pathogenetic mechanisms remain unknown. In this “Data in Brief” paper, we sum up the whole genome analysis by mRNA sequencing of normal and DS induced pluripotent stem cells that was recently published by Hibaoui et al. in EMBO molecular medicine.http://www.sciencedirect.com/science/article/pii/S2213596014000646Induced pluripotent stem cellsDown syndromeChromosome 21mRNA sequencing |
| spellingShingle | Youssef Hibaoui Iwona Grad Audrey Letourneau Federico A. Santoni Stylianos E. Antonarakis Anis Feki Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 Genomics Data Induced pluripotent stem cells Down syndrome Chromosome 21 mRNA sequencing |
| title | Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 |
| title_full | Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 |
| title_fullStr | Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 |
| title_full_unstemmed | Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 |
| title_short | Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 |
| title_sort | data in brief transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 |
| topic | Induced pluripotent stem cells Down syndrome Chromosome 21 mRNA sequencing |
| url | http://www.sciencedirect.com/science/article/pii/S2213596014000646 |
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