Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility
Objectives: Spinal cord injury (SCI) often occurs in young adult men. Factors such as erectile and ejaculation dysfunction and abnormal anomalies may contribute to the incidence of infertility. In healthy men, there is a balance between reactive oxygen species (ROS) and antioxidant scavenging system...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Aras Part Medical International Press
2019-07-01
|
| Series: | Crescent Journal of Medical and Biological Sciences |
| Subjects: | |
| Online Access: | http://www.cjmb.org/pdf.php?id=254 |
| _version_ | 1817991051717115904 |
|---|---|
| author | Soheila Bani Parviz Shahabi Jalal Abdolalizadeh Iraj Lotfinia Amir Vahedi Meysam Ghorbani Amir Shakouri |
| author_facet | Soheila Bani Parviz Shahabi Jalal Abdolalizadeh Iraj Lotfinia Amir Vahedi Meysam Ghorbani Amir Shakouri |
| author_sort | Soheila Bani |
| collection | DOAJ |
| description | Objectives: Spinal cord injury (SCI) often occurs in young adult men. Factors such as erectile and ejaculation dysfunction and abnormal anomalies may contribute to the incidence of infertility. In healthy men, there is a balance between reactive oxygen species (ROS) and antioxidant scavenging systems and antioxidants have a positive impact on male fertility. Therefore, the present study examined the findings of different review studies on the role of oxidative stress (OS) and antioxidants in reducing the sperm function and treating the sperm components, respectively. Materials and Methods: The relevant keywords were used to search for related articles in different databases such as Medline, PubMed, ISI, Scopus, and Google Scholar, which resulted in retrieving 28 articles about OS, antioxidants, DNA damage, apoptosis, and sperm parameters. Results: Based on the findings of previous studies, antioxidant supplementation improved the number, motility, morphology, and the DNA integrity of the sperm. In addition, the combination of several antioxidants was found to perform better compared to using only one antioxidant. Conclusions: In general, the heightened levels of uncontrolled OS is modified through the antioxidant supplements or their combination. Therefore, antioxidant supplementation can be considered in the treatment of infertile men. |
| first_indexed | 2024-04-14T01:08:02Z |
| format | Article |
| id | doaj.art-398c86ebe82d4fb4abc262565a9720c5 |
| institution | Directory Open Access Journal |
| issn | 2148-9696 |
| language | English |
| last_indexed | 2024-04-14T01:08:02Z |
| publishDate | 2019-07-01 |
| publisher | Aras Part Medical International Press |
| record_format | Article |
| series | Crescent Journal of Medical and Biological Sciences |
| spelling | doaj.art-398c86ebe82d4fb4abc262565a9720c52022-12-22T02:21:10ZengAras Part Medical International PressCrescent Journal of Medical and Biological Sciences2148-96962019-07-0163253266cjmb-5045Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male FertilitySoheila Bani0Parviz Shahabi1Jalal Abdolalizadeh2Iraj Lotfinia3Amir Vahedi4Meysam Ghorbani5Amir Shakouri6Neuroscience Research Center, Nursing and midwifery faculty, Tabriz University of Medical Sciences, Iran.Neuroscience Research Center, Medical Faculty, Tabriz University of Medical Sciences, Iran.Drug Applied Research Center, Parmedicine Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.Neuroscience Research Center, Medical Faculty, Tabriz University of Medical Sciences, Iran.Department of Pathology, Tabriz University of Medical Sciences, Tabriz, Iran.Neuroscience Research Center, Medical Faculty, Tabriz University of Medical Sciences, Iran.Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Objectives: Spinal cord injury (SCI) often occurs in young adult men. Factors such as erectile and ejaculation dysfunction and abnormal anomalies may contribute to the incidence of infertility. In healthy men, there is a balance between reactive oxygen species (ROS) and antioxidant scavenging systems and antioxidants have a positive impact on male fertility. Therefore, the present study examined the findings of different review studies on the role of oxidative stress (OS) and antioxidants in reducing the sperm function and treating the sperm components, respectively. Materials and Methods: The relevant keywords were used to search for related articles in different databases such as Medline, PubMed, ISI, Scopus, and Google Scholar, which resulted in retrieving 28 articles about OS, antioxidants, DNA damage, apoptosis, and sperm parameters. Results: Based on the findings of previous studies, antioxidant supplementation improved the number, motility, morphology, and the DNA integrity of the sperm. In addition, the combination of several antioxidants was found to perform better compared to using only one antioxidant. Conclusions: In general, the heightened levels of uncontrolled OS is modified through the antioxidant supplements or their combination. Therefore, antioxidant supplementation can be considered in the treatment of infertile men.http://www.cjmb.org/pdf.php?id=254spinal cord injuryoxidative stressantioxidantsmen fertility |
| spellingShingle | Soheila Bani Parviz Shahabi Jalal Abdolalizadeh Iraj Lotfinia Amir Vahedi Meysam Ghorbani Amir Shakouri Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility Crescent Journal of Medical and Biological Sciences spinal cord injury oxidative stress antioxidants men fertility |
| title | Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility |
| title_full | Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility |
| title_fullStr | Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility |
| title_full_unstemmed | Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility |
| title_short | Spinal Cord Injury‚ Oxidative Stress, and Antioxidants: Impact on Male Fertility |
| title_sort | spinal cord injury oxidative stress and antioxidants impact on male fertility |
| topic | spinal cord injury oxidative stress antioxidants men fertility |
| url | http://www.cjmb.org/pdf.php?id=254 |
| work_keys_str_mv | AT soheilabani spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility AT parvizshahabi spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility AT jalalabdolalizadeh spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility AT irajlotfinia spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility AT amirvahedi spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility AT meysamghorbani spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility AT amirshakouri spinalcordinjuryoxidativestressandantioxidantsimpactonmalefertility |