Effect of cyclic substituents on the anti-cancer activity and DNA interaction of ruthenium(II) bis-phenanthroline dipyridoquinoline
Introduction: Ruthenium(II) complexes have emerged recently as candidates for anti-cancer therapy, where activity is related to lipohilicity, cellular localization, and specific interactions with biomolecules.Methods: In this work, two novel complexes were synthesized and are reported based on the [...
Main Authors: | Etubonesi E. Nyong-Bassey, Andrew L. Hicks, Poppy Bergin, Eimer M. Tuite, Valery Kozhevnikov, Stephany Veuger |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-10-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2023.1252285/full |
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