Oxygen-linked S-nitrosation in fish myoglobins: a cysteine-specific tertiary allosteric effect.
The discovery that cysteine (Cys) S-nitrosation of trout myoglobin (Mb) increases heme O2 affinity has revealed a novel allosteric effect that may promote hypoxia-induced nitric oxide (NO) delivery in the trout heart and improve myocardial efficiency. To better understand this allosteric effect, we...
Main Authors: | Signe Helbo, Andrew J Gow, Amna Jamil, Barry D Howes, Giulietta Smulevich, Angela Fago |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4039430?pdf=render |
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